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Genome engineering

The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos

Kei Miyamoto, Ken-ichi T. Suzuki, Miyuki Suzuki, Yuto Sakane, Tetsushi Sakuma, Sarah Herberg, Angela Simeone, David Simpson, Jerome Jullien, Takashi Yamamoto, J. B. Gurdon

published 18 Nov 2015

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Simple Genome Editing of Rodent Intact Embryos by Electroporation

Takehito Kaneko, Tomoji Mashimo

published 10 Nov 2015

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klf2a^sh317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes

Peter Novodvorsky, Oliver Watson, Caroline Gray, Robert N. Wilkinson, Scott Reeve, Carl Smythe, Richard Beniston, Karen Plant, Richard Maguire, Alexander M. K. Rothman, Stone Elworthy, Fredericus J. M. van Eeden, Timothy J. A. Chico

published 27 Oct 2015

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Complete Genome Sequence of Thermus aquaticus Y51MC23

Phillip J. Brumm, Scott Monsma, Brendan Keough, Svetlana Jasinovica, Erin Ferguson, Thomas Schoenfeld, Michael Lodes, David A. Mead

published 14 Oct 2015

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Antimicrobial Resistance and Molecular Investigation of H₂S-Negative Salmonella enterica subsp. enterica serovar Choleraesuis Isolates in China

Jing Xie, Shengjie Yi, Jiangong Zhu, Peng Li, Beibei Liang, Hao Li, Xiaoxia Yang, Ligui Wang, Rongzhang Hao, Leili Jia, Zhihao Wu, Shaofu Qiu, Hongbin Song

published 02 Oct 2015

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Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome

Mark C. Wallen, Thomas Gaj, Carlos F. Barbas III

published 28 Sep 2015

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Comparative Analysis of the Orphan CRISPR2 Locus in 242 Enterococcus faecalis Strains

Karthik Hullahalli, Marinelle Rodrigues, Brendan D. Schmidt, Xiang Li, Pooja Bhardwaj, Kelli L. Palmer

published 23 Sep 2015

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Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells

Erin H. Breese, Corina Buechele, Catherine Dawson, Michael L. Cleary, Matthew H. Porteus

published 09 Sep 2015

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Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug Screening

Warunee Dansithong, Sharan Paul, Daniel R. Scoles, Stefan M. Pulst, Duong P. Huynh

published 28 Aug 2015

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CRISPR/Cas9-Mediated Genome Editing in Soybean Hairy Roots

Yupeng Cai, Li Chen, Xiujie Liu, Shi Sun, Cunxiang Wu, Bingjun Jiang, Tianfu Han, Wensheng Hou

published 18 Aug 2015

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Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium

Alexandra E. Briner, Gabriele Andrea Lugli, Christian Milani, Sabrina Duranti, Francesca Turroni, Miguel Gueimonde, Abelardo Margolles, Douwe van Sinderen, Marco Ventura, Rodolphe Barrangou

published 31 Jul 2015

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Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering

Mustapha Aouida, Ayman Eid, Zahir Ali, Thomas Cradick, Ciaran Lee, Harshavardhan Deshmukh, Ahmed Atef, Dina AbuSamra, Samah Zeineb Gadhoum, Jasmeen Merzaban, Gang Bao, Magdy Mahfouz

published 30 Jul 2015

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A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish

Zlatko Radev, Jean-Michel Hermel, Yannick Elipot, Sandrine Bretaud, Sylvain Arnould, Philippe Duchateau, Florence Ruggiero, Jean-Stéphane Joly, Frédéric Sohm

published 29 Jul 2015

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