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Genome engineering

A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions

Victoria B. Stockman, Lila Ghamsari, Gorka Lasso, Barry Honig, Sagi D. Shapira, Harris H. Wang

published 09 Dec 2016

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Reactivation of FMR1 by CRISPR/Cas9-Mediated Deletion of the Expanded CGG-Repeat of the Fragile X Chromosome

Nina Xie, He Gong, Joshua A. Suhl, Pankaj Chopra, Tao Wang, Stephen T. Warren

published 21 Oct 2016

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Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans

Samantha D. M. Arras, Sheena M. H. Chua, Maha S. I. Wizrah, Joshua A. Faint, Amy S. Yap, James A. Fraser

published 06 Oct 2016

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Generation of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System

Tao Zhang, Yajun Yin, Huan Liu, Weili Du, Chonghua Ren, Ling Wang, Hongzhao Lu, Zhiying Zhang

published 29 Sep 2016

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Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors

Scott B. Vafai, Emily Mevers, Kathleen W. Higgins, Yevgenia Fomina, Jianming Zhang, Anna Mandinova, David Newman, Stanley Y. Shaw, Jon Clardy, Vamsi K. Mootha

published 13 Sep 2016

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Mapping the Emergence of Synthetic Biology

Benjamin Raimbault, Jean-Philippe Cointet, Pierre-Benoît Joly

published 09 Sep 2016

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Diversity in a Polymicrobial Community Revealed by Analysis of Viromes, Endolysins and CRISPR Spacers

Michelle Davison, Todd J. Treangen, Sergey Koren, Mihai Pop, Devaki Bhaya

published 09 Sep 2016

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Molecular Characterization of Salmonella enterica Serovar Aberdeen Negative for H₂S Production in China

Fuli Wu, Xuebin Xu, Jing Xie, Shengjie Yi, Jian Wang, Xiaoxia Yang, Chaojie Yang, Beibei Liang, Qiuxia Ma, Hao Li, Hongbin Song, Shaofu Qiu

published 23 Aug 2016

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The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging

Barbara Dupret, Pamela Völkel, Xuefen Le Bourhis, Pierre-Olivier Angrand

published 21 Jul 2016

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Targeted Mutagenesis of the Hypophysiotropic Gnrh3 in Zebrafish (Danio rerio) Reveals No Effects on Reproductive Performance

Olivia Smith Spicer, Ten-Tsao Wong, Nilli Zmora, Yonathan Zohar

published 29 Jun 2016

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Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Hongmei Zhu, Jun Liu, Chenchen Cui, Yujie Song, Hengtao Ge, Linyong Hu, Qian Li, Yaping Jin, Yong Zhang

published 03 Jun 2016

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Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes

Anil K. Challa, Evan R. Boitet, Ashley N. Turner, Larry W. Johnson, Daniel Kennedy, Ethan R. Downs, Katherine M. Hymel, Alecia K. Gross, Robert A. Kesterson

published 25 May 2016

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Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA

Thomas J. Stoddard, Benjamin M. Clasen, Nicholas J. Baltes, Zachary L. Demorest, Daniel F. Voytas, Feng Zhang, Song Luo

published 13 May 2016

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