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Genome engineering

Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening

Jenille Tan, Scott E. Martin

A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions

Victoria B. Stockman, Lila Ghamsari, [ ... ], Harris H. Wang

Reactivation of FMR1 by CRISPR/Cas9-Mediated Deletion of the Expanded CGG-Repeat of the Fragile X Chromosome

Nina Xie, He Gong, [ ... ], Stephen T. Warren

Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans

Samantha D. M. Arras, Sheena M. H. Chua, [ ... ], James A. Fraser

Generation of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System

Tao Zhang, Yajun Yin, [ ... ], Zhiying Zhang

Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors

Scott B. Vafai, Emily Mevers, [ ... ], Vamsi K. Mootha

Mapping the Emergence of Synthetic Biology

Benjamin Raimbault, Jean-Philippe Cointet, Pierre-Benoît Joly

Diversity in a Polymicrobial Community Revealed by Analysis of Viromes, Endolysins and CRISPR Spacers

Michelle Davison, Todd J. Treangen, [ ... ], Devaki Bhaya

Molecular Characterization of Salmonella enterica Serovar Aberdeen Negative for H₂S Production in China

Fuli Wu, Xuebin Xu, [ ... ], Shaofu Qiu

The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging

Barbara Dupret, Pamela Völkel, Xuefen Le Bourhis, Pierre-Olivier Angrand

Targeted Mutagenesis of the Hypophysiotropic Gnrh3 in Zebrafish (Danio rerio) Reveals No Effects on Reproductive Performance

Olivia Smith Spicer, Ten-Tsao Wong, Nilli Zmora, Yonathan Zohar

Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Hongmei Zhu, Jun Liu, [ ... ], Yong Zhang

Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes

Anil K. Challa, Evan R. Boitet, [ ... ], Robert A. Kesterson

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