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Genome engineering

Comparative pathogenomics of Clostridium tetani

Jonathan E. Cohen, Rong Wang, [ ... ], James E. Keller

Using local chromatin structure to improve CRISPR/Cas9 efficiency in zebrafish

Yunru Chen, Shiyang Zeng, [ ... ], Yong Zhang

IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection

Qian Zhang, Lei-Ping Zeng, [ ... ], Lin-Fa Wang

Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells

Shinsaku Tokuda, Toyohiro Hirai, Mikio Furuse

Zygotic vinculin is not essential for embryonic development in zebrafish

Mitchell K. L. Han, Gerard N. M. van der Krogt, Johan de Rooij

CRISPRpred: A flexible and efficient tool for sgRNAs on-target activity prediction in CRISPR/Cas9 systems

Md. Khaledur Rahman, M. Sohel Rahman

Reversible perturbations of gene regulation after genome editing in Drosophila cells

Stefan Kunzelmann, Klaus Förstemann

In silico genomic insights into aspects of food safety and defense mechanisms of a potentially probiotic Lactobacillus pentosus MP-10 isolated from brines of naturally fermented Aloreña green table olives

Hikmate Abriouel, Beatriz Pérez Montoro, [ ... ], Nabil Benomar

Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells

Sanne Hindriksen, Arne J. Bramer, [ ... ], Michael A. Hadders

No evidence for genome editing in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi Argonaute (NgAgo)

Nay Chi Khin, Jenna L. Lowe, Lora M. Jensen, Gaetan Burgio

Detection of genome-edited mutant clones by a simple competition-based PCR method

Takeshi Harayama, Howard Riezman

Frameshift indels introduced by genome editing can lead to in-frame exon skipping

Simon Lalonde, Oliver A. Stone, [ ... ], Guillaume Lettre

Plasmid-free CRISPR/Cas9 genome editing in Plasmodium falciparum confirms mutations conferring resistance to the dihydroisoquinolone clinical candidate SJ733

Emily D. Crawford, Jenai Quan, [ ... ], Joseph L. DeRisi

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