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Genetics of disease

Phenome-wide screening of the putative causal determinants of bipolar affective disorder using genetic data

Bin Hu, Qi Zhou, Hao Wu, Dejiang Yang, Chongyu Xiong, Xiaowei Zhang

published 02 Jan 2026

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To test or not to test? Study protocol for a best-worst scaling to understand decision-making and preferences for genetic testing in moderate-risk individuals

Carina Oedingen, Nicolle Hua, Karen V. MacDonald, Julien Marcadier, Renee Perrier, Lindsay Tuer, Brenda McInnes, Francois Bernier, Deborah A. Marshall

published 29 Dec 2025

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Gender difference in self-reported empathy: Effects of task instructions and exposure to gender essentialism primes

Namitha Rajasekhar, Anna Redly, Shevantika Nanda, Gillian R. Brown

published 12 Dec 2025

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Exploring the genetic frontier: Unraveling ANRIL, PAI-1, and HNF1α in stroke progression

Abdullah Hamadi, Rashid Mir, Osama M. Al-Amer, Mohammed Alasseiri, Gasim Dobie, Imadeldin Elfaki, Waseem AlZamzami, Sael Alatawi, Atif Abdulwahab A. Oyouni, Mohammad A. Alanazi, Saravanan Muthupandian

published 11 Dec 2025

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Using pre-training and interaction modeling for ancestry-specific disease prediction using multiomics data from the UK Biobank

Thomas Le Menestrel, Erin Craig, Robert Tibshirani, Trevor Hastie, Manuel Rivas

published 01 Dec 2025

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A multilayered genetic structure analysis between inflammatory bowel disease and bone density/osteoporosis

Mengting Qin, Xinhong Liu, Qinghua Luo, Ruyun Cai

published 20 Nov 2025

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Associations of perceived neighborhood factors and Alzheimer’s disease polygenic score with cognition: Evidence from the Health and Retirement Study

Erin B. Ware, Peiyao Zhu, Grace Noppert, Mingzhou Fu, Mikayla Benbow, Lindsay C. Kobayashi, Lindsay H. Ryan, Kelly M. Bakulski

published 20 Nov 2025

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Genetic correlation analysis between sepsis and hematological traits: Identifying shared genomic regions

Jianmin Zhang, Miao Hou, Zhenjiang Bai, Jian Wang, Jie Huang

published 14 Nov 2025

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Elucidation and application of the neuroimmune axis between depression and autoimmune diseases: A genome wide and cohort study

Fu Sun, Shirong Hui, Bin Gong, Jinhua Gu, Peng Huang

published 10 Nov 2025

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Association of erythropoietin gene polymorphism (rs1617640 C>T/G) with diabetic retinopathy in Type 2 diabetes mellitus patients of Punjabi population in Pakistan

Cyrollah Disoma, Aqsa Malik, Ayesha Nisar, Inam Ullah, Sikandar Hayat, Abdul Qadeer, Sardar Azhar Mehmood, Sawar Khan, Zanxian Xia

published 06 Nov 2025

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Mapping the state-of-the-art of the barriers for personalized preventive approaches worldwide: A scoping review of reviews

Nicolò Scarsi, Abdelrahman Taha, Sara Farina, Tommaso Osti, Luigi Russo, Alessandra Maio, Roberta Pastorino, Stefania Boccia

published 24 Oct 2025

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Investigating the common genetic basis between inflammatory bowel disease and metabolic syndrome through genomic structural equation modeling

Pan Shen, Hao Xiong, Qing-Hua Luo, Yi-Fan Ding, Wei Ge, Wu Liao, Lei-Chang Zhang

published 16 Oct 2025

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Analyzing real-world adverse events of spironolactone with the FAERS database

Guowei Lin, Ru Chen, Chaoning Wen, Zhuopin Li, Xiangshan Yan, Lixian Li

published 17 Sep 2025

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