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Genetic predisposition

Analysis of Genetic and Environmental Risk Factors and Their Interactions in Korean Patients with Age-Related Macular Degeneration

Se Joon Woo, Jeeyun Ahn, Margaux A. Morrison, So Yeon Ahn, Jaebong Lee, Ki Woong Kim, Margaret M. DeAngelis, Kyu Hyung Park

published 14 Jul 2015

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Genetic Variants of IκB Kinase β (IKBKB) and Polymerase β (POLB) Were Not Associated with Systemic Lupus Erythematosus Risk in a Chinese Han Population

Yuan Li, Ziyan Wu, Shulan Zhang, Si Chen, Ping Li, Jing Li, Chongwei Cao, Bin Liu, Fengchun Zhang, Yongzhe Li

published 13 Jul 2015

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Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume

Ayush Giri, Todd L. Edwards, Saundra S. Motley, Susan H. Byerly, Jay H. Fowke

published 09 Jul 2015

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Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk

Celia G. Walker, Ivonne Solis-Trapala, Christina Holzapfel, Gina L. Ambrosini, Nicholas R. Fuller, Ruth J. F. Loos, Hans Hauner, Ian D. Caterson, Susan A. Jebb

published 08 Jul 2015

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CFH Y402H and ARMS2 A69S Polymorphisms and Oral Supplementation with Docosahexaenoic Acid in Neovascular Age-Related Macular Degeneration Patients: The NAT2 Study

Bénédicte M. J. Merle, Florence Richard, Pascale Benlian, Nathalie Puche, Cécile Delcourt, Eric H. Souied

published 01 Jul 2015

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ABC Transporters and the Proteasome Complex Are Implicated in Susceptibility to Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis across Multiple Drugs

Paola Nicoletti, Mukesh Bansal, Celine Lefebvre, Paolo Guarnieri, Yufeng Shen, Itsik Pe’er, Andrea Califano, Aris Floratos

published 25 Jun 2015

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A Weighted Polygenic Risk Score Using 14 Known Susceptibility Variants to Estimate Risk and Age Onset of Psoriasis in Han Chinese

Xianyong Yin, Hui Cheng, Yan Lin, Nathan E. Wineinger, Fusheng Zhou, Yujun Sheng, Chao Yang, Pan Li, Feng Li, Changbing Shen, Sen Yang, Nicholas J. Schork, Xuejun Zhang

published 01 May 2015

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No Additional Prognostic Value of Genetic Information in the Prediction of Vascular Events after Cerebral Ischemia of Arterial Origin: The PROMISe Study

Sefanja Achterberg, L. Jaap Kappelle, Paul I. W. de Bakker, Matthew Traylor, Ale Algra, SMART Study Group and the METASTROKE Consortium

published 23 Apr 2015

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The Association between Carbohydrate-Rich Foods and Risk of Cardiovascular Disease Is Not Modified by Genetic Susceptibility to Dyslipidemia as Determined by 80 Validated Variants

Emily Sonestedt, Sophie Hellstrand, Christina-Alexandra Schulz, Peter Wallström, Isabel Drake, Ulrika Ericson, Bo Gullberg, Bo Hedblad, Marju Orho-Melander

published 21 Apr 2015

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PITX2 Loss-of-Function Mutation Contributes to Congenital Endocardial Cushion Defect and Axenfeld-Rieger Syndrome

Cui-Mei Zhao, Lu-Ying Peng, Li Li, Xing-Yuan Liu, Juan Wang, Xian-Ling Zhang, Fang Yuan, Ruo-Gu Li, Xing-Biao Qiu, Yi-Qing Yang

published 20 Apr 2015

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Can Data Science Inform Environmental Justice and Community Risk Screening for Type 2 Diabetes?

J. Allen Davis, Lyle D. Burgoon

published 14 Apr 2015

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Common Variants of KCNJ10 Are Associated with Susceptibility and Anti-Epileptic Drug Resistance in Chinese Genetic Generalized Epilepsies

Yong Guo, Kui Po Yan, Qiang Qu, Jian Qu, Zi Gui Chen, Tao Song, Xiang-Ying Luo, Zhong-Yi Sun, Chang-Long Bi, Jin-Fang Liu

published 13 Apr 2015

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Genotype-Property Patient-Phenotype Relations Suggest that Proteome Exhaustion Can Cause Amyotrophic Lateral Sclerosis

Kasper P. Kepp

published 23 Mar 2015

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