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Genetic interference

TAL Effectors Target the C-Terminal Domain of RNA Polymerase II (CTD) by Inhibiting the Prolyl-Isomerase Activity of a CTD-Associated Cyclophilin

Mariane Noronha Domingues, Bruna Medeia de Campos, Maria Luiza Peixoto de Oliveira, Uli Quirino de Mello, Celso Eduardo Benedetti

published 20 Jul 2012

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A Wnt/beta-Catenin Pathway Antagonist Chibby Binds Cenexin at the Distal End of Mother Centrioles and Functions in Primary Cilia Formation

Nathan Steere, Vanessa Chae, Michael Burke, Feng-Qian Li, Ken-Ichi Takemaru, Ryoko Kuriyama

published 20 Jul 2012

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The LKB1 Tumor Suppressor Controls Spindle Orientation and Localization of Activated AMPK in Mitotic Epithelial Cells

Chongjuan Wei, Varun Kumar Bhattaram, John C. Igwe, Elizabeth Fleming, Jennifer S. Tirnauer

published 18 Jul 2012

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STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway

Nelson W. Chong, Andrea L. Koekemoer, Samir Ounzain, Nilesh J. Samani, Jordan T. Shin, Stanley Y. Shaw

published 18 Jul 2012

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Novel RNAi-Mediated Approach to G Protein-Coupled Receptor Deorphanization: Proof of Principle and Characterization of a Planarian 5-HT Receptor

Mostafa Zamanian, Prince N. Agbedanu, Nicolas J. Wheeler, Paul McVeigh, Michael J. Kimber, Tim A. Day

published 18 Jul 2012

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Microtubules and Lis-1/NudE/Dynein Regulate Invasive Cell-on-Cell Migration in Drosophila

Nachen Yang, Mikiko Inaki, Adam Cliffe, Pernille Rørth

published 13 Jul 2012

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Cigarette Smoke Modulates Expression of Human Rhinovirus-Induced Airway Epithelial Host Defense Genes

David Proud, Magdalena H. Hudy, Shahina Wiehler, Raza S. Zaheer, Minaa A. Amin, Jonathan B. Pelikan, Claire E. Tacon, Tabitha O. Tonsaker, Brandie L. Walker, Cora Kooi, Suzanne L. Traves, Richard Leigh

published 12 Jul 2012

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Identification of a Novel Function for the Chromatin Remodeling Protein ING2 in Muscle Differentiation

Shawn A. Eapen, Stuart J. Netherton, Krishna P. Sarker, Lili Deng, Angela Chan, Karl Riabowol, Shirin Bonni

published 12 Jul 2012

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A Genetic Validation Study Reveals a Role of Vitamin D Metabolism in the Response to Interferon-Alfa-Based Therapy of Chronic Hepatitis C

Christian M. Lange, Stephanie Bibert, Zoltan Kutalik, Philippe Burgisser, Andreas Cerny, Jean-Francois Dufour, Andreas Geier, Tilman J. Gerlach, Markus H. Heim, Raffaele Malinverni, Francesco Negro, Stephan Regenass, Klaus Badenhoop, Jörg Bojunga, Christoph Sarrazin, Stefan Zeuzem, Tobias Müller, Thomas Berg, Pierre-Yves Bochud, Darius Moradpour, the Swiss Hepatitis C Cohort Study Group

published 12 Jul 2012

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Localization and Sub-Cellular Shuttling of HTLV-1 Tax with the miRNA Machinery

Rachel Van Duyne, Irene Guendel, Zachary Klase, Aarthi Narayanan, William Coley, Elizabeth Jaworski, Jessica Roman, Anastas Popratiloff, Renaud Mahieux, Kylene Kehn-Hall, Fatah Kashanchi

published 10 Jul 2012

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Identification of a Polyketide Synthase Required for Alternariol (AOH) and Alternariol-9-Methyl Ether (AME) Formation in Alternaria alternata

Debjani Saha, Ramona Fetzner, Britta Burkhardt, Joachim Podlech, Manfred Metzler, Ha Dang, Christopher Lawrence, Reinhard Fischer

published 06 Jul 2012

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Large Isoforms of UNC-89 (Obscurin) Are Required for Muscle Cell Architecture and Optimal Calcium Release in Caenorhabditis elegans

Patrick M. Spooner, Jennifer Bonner, Andres V. Maricq, Guy M. Benian, Kenneth R. Norman

published 02 Jul 2012

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A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans

Mark T. Miedel, Nathan J. Graf, Kate E. Stephen, Olivia S. Long, Stephen C. Pak, David H. Perlmutter, Gary A. Silverman, Cliff J. Luke

published 02 Jul 2012

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