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Genetic interference

HTS-Net: An integrated regulome-interactome approach for establishing network regulation models in high-throughput screenings

Claire Rioualen, Quentin Da Costa, Bernard Chetrit, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Ghislain Bidaut

published 26 Sep 2017

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Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

Justin Hall, Amy Brault, Fabien Vincent, Shawn Weng, Hong Wang, Darren Dumlao, Ann Aulabaugh, Dikran Aivazian, Dana Castro, Ming Chen, Jeffrey Culp, Ken Dower, Joseph Gardner, Steven Hawrylik, Douglas Golenbock, David Hepworth, Mark Horn, Lyn Jones, Peter Jones, Eicke Latz, Jing Li, Lih-Ling Lin, Wen Lin, David Lin, Frank Lovering, Nootaree Niljanskul, Ryan Nistler, Betsy Pierce, Olga Plotnikova, Daniel Schmitt, Suman Shanker, James Smith, William Snyder, Timothy Subashi, John Trujillo, Edyta Tyminski, Guoxing Wang, Jimson Wong, Bruce Lefker, Leslie Dakin, Karen Leach

published 21 Sep 2017

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Inhibition of infection spread by co-transmitted defective interfering particles

Ashley Baltes, Fulya Akpinar, Bahar Inankur, John Yin

published 15 Sep 2017

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The spliceosome-associated protein Mfap1 binds to VCP in Drosophila

Sandra Rode, Henrike Ohm, Jaqueline Zipfel, Sebastian Rumpf

published 24 Aug 2017

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Lissencephaly-1 dependent axonal retrograde transport of L1-type CAM Neuroglian in the adult drosophila central nervous system

Sirisha R. Kudumala, Tyrone Penserga, Jana Börner, Olesya Slipchuk, Priyanka Kakad, LaTasha H. Lee, Aater Qureshi, Jan Pielage, Tanja A. Godenschwege

published 24 Aug 2017

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HSF-1 is a regulator of miRNA expression in Caenorhabditis elegans

Jessica Brunquell, Alana Snyder, Feng Cheng, Sandy D. Westerheide

published 24 Aug 2017

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The loss and recovery of vertebrate vision examined in microplates

Robert J. Thorn, Danielle E. Clift, Oladele Ojo, Ruth M. Colwill, Robbert Creton

published 17 Aug 2017

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Immunohistochemical analysis reveals variations in proteasome tissue expression in C. elegans

Elisa Mikkonen, Caj Haglund, Carina I. Holmberg

published 17 Aug 2017

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Stronger selection can slow down evolution driven by recombination on a smooth fitness landscape

Masahiko Ueda, Nobuto Takeuchi, Kunihiko Kaneko

published 15 Aug 2017

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Optimization of recombinant bacteria expressing dsRNA to enhance insecticidal activity against a lepidopteran insect, Spodoptera exigua

Mohammad Vatanparast, Yonggyun Kim

published 11 Aug 2017

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Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells

Olaf Voets, Frans Tielen, Edo Elstak, Julian Benschop, Max Grimbergen, Jan Stallen, Richard Janssen, Andre van Marle, Christian Essrich

published 11 Aug 2017

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Development of transgenic Brassica juncea lines for reduced seed sinapine content by perturbing phenylpropanoid pathway genes

Sachin Kajla, Arundhati Mukhopadhyay, Akshay K. Pradhan

published 07 Aug 2017

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Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization

Jean-Louis Couderc, Graziella Richard, Caroline Vachias, Vincent Mirouse

published 02 Aug 2017

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