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Gene targeting

Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Hongmei Zhu, Jun Liu, [ ... ], Yong Zhang

Unravelling the Secrets of Mycobacterial Cidality through the Lens of Antisense

Parvinder Kaur, Santanu Datta, [ ... ], Sudha Ramaiah

Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9

Lech Kaczmarczyk, Ylva Mende, Branko Zevnik, Walker S. Jackson

Generation of an Oocyte-Specific Cas9 Transgenic Mouse for Genome Editing

Linlin Zhang, Jiankui Zhou, [ ... ], Xin Lou

Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells

Lazar Dimitrov, Darlene Pedersen, [ ... ], Philip A. Leighton

Identification of Genome-Wide Variants and Discovery of Variants Associated with Brassica rapa Clubroot Resistance Gene Rcr1 through Bulked Segregant RNA Sequencing

Fengqun Yu, Xingguo Zhang, [ ... ], Gary Peng

The Trypanosoma cruzi Diamine Transporter Is Essential for Robust Infection of Mammalian Cells

Marie-Pierre Hasne, Radika Soysa, Buddy Ullman

PCR-Based Seamless Genome Editing with High Efficiency and Fidelity in Escherichia coli

Yilan Liu, Maohua Yang, [ ... ], Yanhe Ma

The pugilistDominant Mutation of Drosophila melanogaster: A Simple-Sequence Repeat Disorder Reveals Localized Transport in the Eye

Yikang S. Rong, Mary M. Golic, Kent G. Golic

Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells

Alan M. Williams, Yaakov Maman, Jukka Alinikula, David G. Schatz

Generation and Characterisation of a Pax8-CreER^T2 Transgenic Line and a Slc22a6-CreER^T2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells

Judit Espana-Agusti, Xiangang Zou, [ ... ], Athena Matakidou

A Tool for Multiple Targeted Genome Deletions that Is Precise, Scar-Free, and Suitable for Automation

Wayne Aubrey, Michael C. Riley, [ ... ], Amanda Clare

Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome

Mark C. Wallen, Thomas Gaj, Carlos F. Barbas III

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