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Gene identification and analysis

Identification of divergent PTPN11 mutations in canine histiocytic sarcomas reveals evidence of an independent clonal origin

Stéphanie Mottier, Armel Houel, Solveig Bouchard, Charline Bianchi, Louis Le Nezet, Richard Guyon, Stéphane Dreano, Thomas Derrien, Jerôme Abadie, Catherine André, Benoît Hédan

published 20 Jul 2026

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Detection of critical transition states in complex diseases based on distance correlation coefficient

Pingjun Hou, Changchun Liu, Xinlin Zhang

published 16 Jul 2026

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Genetic surveillance of first- and second-line drug-resistant isolates of Mycobacterium tuberculosis in Peru

David Santos-Lázaro, Aiko N. Vigo, Vidia V. Cotrina, Sandra Villar, Alexis Medina, Cynthia Julcapoma, Edson Pacheco, Miriam J. Alarcón, Zully M. Puyén

published 09 Jul 2026

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A clinical pilot study for personalized risk-based breast cancer screening utilizing a polygenic risk score

Tone Hovda, Siim Sober, Peeter Padrik, Krista Kruuv-Kao, Eli Marie Grindedal, Tone Bøe Aaman Vamre, Eline Eikeland, Solveig Hofvind, Kristine Kleivi Sahlberg

published 08 Jul 2026

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Somatic mutation profiles in aged military nuclear test veterans: A comparative whole-genome sequence study

Justin Ofosu-Dankwa, Cristina Sisu, Rhona M. Anderson

published 30 Jun 2026

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Bioinformatics analysis of pyroptosis-related differentially expressed genes in sepsis and diabetes mellitus

Mengxuan Liu, Haiyan Song, Can Zhang, Jiaxin Li, Meng Han, Ying Li

published 25 Jun 2026

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Identification and diagnostic potential of pyroptosis-related genes in endometriosis: A novel bioinformatics analysis and validation

Li Wang, Piaopiao Teng, Jiawen Chen, Caiyun Ding, Xianchen Luo, Chang Su, Guantai Ni, Yuanyuan Lyu, Jin Ding

published 09 Jun 2026

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Transcriptome sequencing combined with experimental verification to explore potential key genes related to uric acid in diabetic retinopathy

Haiming Liang, Tianqi Yang, Feina Lu, Lixia Lin, Hao Liang

published 02 Jun 2026

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GSEA and the coexpression network approach identify novel pathway connections of molecular processes affected in Porto-sinusoidal vascular disease

Aishwarya Iyer, Cenna Doornbos, Chris Evelo, Martina Kutmon, Friederike Ehrhart

published 29 May 2026

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Integrative transcriptomic analysis identifies immune-associated candidate genes and altered immune cell infiltration in pulmonary arterial hypertension

Xitong Yang, Bin Zhou, Ying Yang, Yu Dong, Jifen Fu, Hong Liu, Xinhua Wu

published 22 May 2026

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Identification of key genes and signaling pathways associated with acute pancreatitis and acute lung injury by bioinformatics analysis

Lingfeng Chen, Fengzhu Guo, Chunlin Hong

published 22 May 2026

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Computational biology exposed a common pathogenic mechanism in influenza A and Guillain-Barré syndrome

Ye Deng, Zhongwen Tang, Qiong Chen, Xujuan Hu, Yingjie Zhang, Meng Chen, Qiongya Wang, Fuli Ren

published 20 May 2026

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Network toxicology and bioinformatics analysis predict potential molecular targets and mechanisms by which sevoflurane and propofol influence type 2 diabetes mellitus

Lili Bai, Ping Li, Lina Zhao

published 18 May 2026

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