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Gene identification and analysis

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

Kelly Lim, Winnie L. Kan, Pramod C. Nair, Monika Kutyna, Angel F. Lopez, Timothy Hercus, David M. Ross, Steven Lane, Chun Yew Fong, Anna Brown, Agnes Yong, David Yeung, Timothy Hughes, Devendra Hiwase, Daniel Thomas

published 19 Sep 2024

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Repeated rebiopsy for detection of EGFR T790M mutation in patients with advanced-stage lung adenocarcinoma: Associated factors and treatment outcomes of Osimertinib

Taeyun Kim, Junsu Choe, Sun Hye Shin, Byeong-Ho Jeong, Kyungjong Lee, Hojoong Kim, Se-Hoon Lee, Sang-Won Um

published 19 Sep 2024

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Identification of pivotal genes and pathways in Chorea-acanthocytosis using comprehensive bioinformatic analysis

Ravinder Sharma, Kiran Yadav, Leeza Monga, Vikas Gupta, Vikas Yadav

published 18 Sep 2024

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Comparative genomic landscape of lower-grade glioma and glioblastoma

Xinxin Sun, Qingbin Jia, Kun Li, Conghui Tian, Lili Yi, Lili Yan, Juan Zheng, Xiaodong Jia, Mingliang Gu

published 29 Aug 2024

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Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay

Dinh Thi Thao, Nguyen Phu Thanh, Dong Van Quyen, Ly Tuan Khai, Le Huu Song, Ngo Tat Trung

published 28 Aug 2024

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The pattern of rpoB gene mutation of Mycobacterium tuberculosis and predictors of rifampicin resistance detected by GeneXpert MTB/RIF assay in Tanzania

Peter Richard Torokaa, Mtebe V. Majigo, Heledy Kileo, Loveness Urio, Mariam R. Mbwana, Mariam C. Monah, Sephord Saul Ntibabara, Jasper Kimambo, Paschal Seleman, Collins Franklin, Robert Balama, Riziki M. Kisonga, Agricola Joachim

published 26 Aug 2024

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A new raspberry ketone synthesis gene RinPKS4 identified in Rubus idaeus L. by transcriptome analysis

Zhimin He, Xihuan Yan, Junxin Zhang, Kang Hu, Mengzhe Ou, Chaojun Wei, Aizhen Yang, Jing Li, Tiran Huang, Mingfeng Yang, Lanqing Ma

published 22 Aug 2024

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A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments

Chang Sik Kim, Jonathan Cairns, Valentina Quarantotti, Bogumil Kaczkowski, Yinhai Wang, Peter Konings, Xiang Zhang

published 20 Aug 2024

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A rapid and easy-to-use spinal muscular atrophy screening tool based on primers with high specificity and amplification efficiency for SMN1 combined with single-stranded tag hybridization assay

Masaki Hirano, Kentaro Sahashi, Yuki Ichikawa, Masahisa Katsuno, Atsushi Natsume

published 01 Aug 2024

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Optimising primary molecular profiling in non-small cell lung cancer

R. D. Schouten, I. Schouten, M. M. F. Schuurbiers, V. van der Noort, R. A. M. Damhuis, E. H. F. M. van der Heijden, J. A. Burgers, N. P. Barlo, A. S. R. van Lindert, K. W. Maas, J. J. G. van den Brand, A. A. J. Smit, J. M. W. van Haarst, B. van der Maat, E. Schuuring, H. Blaauwgeers, S. M. Willems, K. Monkhorst, D. van den Broek, M. M. van den Heuvel

published 31 Jul 2024

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Key extracellular proteins and TF-miRNA co-regulatory network in diabetic foot ulcer: Bioinformatics and experimental insights

Guanlin Lin, Ximing Liu

published 22 Jul 2024

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Identification of key genes associated with acute myocardial infarction using WGCNA and two-sample mendelian randomization study

Xiaohe Yang, Yingtao Huang, Dadong Tang, Liangming Yue

published 18 Jul 2024

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Sparse spectral graph analysis and its application to gastric cancer drug resistance-specific molecular interplays identification

Heewon Park, Satoru Miyano

published 05 Jul 2024

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