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Gene expression and vector techniques

Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo

Yoji Tsugawa, Kentaro Furukawa, Tomoko Ise, Masahiro Takayama, Takeshi Ota, Takayuki Kuroda, Shinya Shano, Takashi Hashimoto, Haruyo Konishi, Takeshi Ishihara, Masaaki Sato, Haruhiko Kamada, Keita Fukao, Takao Shishido, Mai Yoshikawa, Tatsuya Takahashi, Satoshi Nagata

published 02 Dec 2024

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Dehydroepiandrosterone inhibits ADAMTS expression via an ERK-dependent mechanism in chondrocytes

Kai Huang, Lin Cheng, Cheng Jiang, Chunwei Zheng, Haili Cai

published 22 Nov 2024

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Pine pollen reverses the function of hepatocellular carcinoma by inhibiting α-Enolase mediated PI3K/AKT signaling pathway

Yanhong Luo, Chun Guo, Caixia Ling, Wenjun Yu, Yuanhong Chen, Lihe Jiang, Qiuxiang Luo, Chunfang Wang, Weixin Xu

published 22 Nov 2024

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Exploring the effects of hypoxia and reoxygenation time on hepatocyte apoptosis and inflammation

Xinlu Xu, Tanfang Zhou, Alimu Tulahong, Rexiati Ruze, Yingmei Shao

published 21 Nov 2024

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The mouse gingiva and HIF-1α, a key gene of hypoxic environment, as tools for post-mortem time estimation

Salomé Mascarell, Coralie Torrens, Caroline Andrique, Asmaa Foda, Tania Delabarde, Bertrand Ludes, Anne-Margaux Collignon, Anne Poliard

published 15 Nov 2024

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Expression of SIGLEC15 correlates with tumor immune infiltration, molecular subtypes, and breast cancer progression

Huan Lai, Yiyang Liu, Yan Gong, Chuanyu Zong, Wei Zeng, Honglei Chen

published 14 Nov 2024

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Comparison of the protein composition of isolated extracellular vesicles from mouse brain and dissociated brain cell culture medium

Zan Xu, Joshua Brian Foster, Rashelle Lashley, Xueqin Wang, Albert John Muhleman, Christopher Eli Masters, Chien-liang Glenn Lin

published 12 Nov 2024

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Post-transcriptional control drives Aurora kinase A expression in human cancers

Roberta Cacioppo, Deniz Rad, Giulia Pagani, Paolo Gandellini, Catherine Lindon

published 11 Nov 2024

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Dolichol kinases from yeast, nematode and human can replace each other and exchange their domains creating active chimeric enzymes in yeast

Danguole Ziogiene, Andrius Burdulis, Albertas Timinskas, Ruta Zinkeviciute, Emilija Vasiliunaite, Milda Norkiene, Alma Gedvilaite

published 07 Nov 2024

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Engineering a probiotic Bacillus subtilis for acetaldehyde removal: A hag locus integration to robustly express acetaldehyde dehydrogenase

Chandler Hassan-Casarez, Valerie Ryan, Bentley M. Shuster, John W. K. Oliver, Zachary D. Abbott

published 07 Nov 2024

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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease

Jian-Ping Yang, Rachel Toughiri, Anshu P. Gounder, Dan Scheibe, Matt Petrus, Sarah J. Fink, Sebastien Vallee, Jon Kenniston, Nikolaos Papaioannou, Steve Langston, Narender R. Gavva, Shane R. Horman

published 06 Nov 2024

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Dietary marine hydrolysate alleviates D-galactose-induced brain aging by attenuating cognitive alterations, oxidative stress and inflammation through the AGE-RAGE axis

Camille Mougin, Mathilde Chataigner, Céline Lucas, Véronique Pallet, Elodie Bouvret, Corinne Joffre, Anne-Laure Dinel

published 24 Oct 2024

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Interplay between de novo and salvage pathways of GDP-fucose synthesis

Edyta Skurska, Mariusz Olczak

published 24 Oct 2024

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