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Gene expression and vector techniques

Overexpression of LINC00672 promotes autophagy in Alzheimer’s disease by upregulating GPNMB

Lingyi Gao, Shijun Hu, Yan Lv, Guoxian Zheng, Zhichuan Lin

published 14 May 2025

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Impact of cardiosphere-derived cells on the maladapted right ventricular muscle in a rat sugen/hypoxia model of pulmonary hypertension with right ventricular dysfunction

Ryan C. Middleton, Oleg A. Karpov, Mario Fournier, Simion Kreimer, Mitra Mastali, Weixin Liu, Liang Li, Norbert F. Voelkel, Jennifer E. Van Eyk, Eduardo Marbán, Michael I. Lewis

published 12 May 2025

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Rubus coreanus extract prevents kidney fibrosis through TGF-β/Smad pathway inhibition

Wencheng Jin, Ara Cho, Bogyeong Cho, Nayeon Shin, Yun Kyu Oh, Chun Soo Lim, Jung Pyo Lee, Jeonghwan Lee

published 12 May 2025

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LncRNA NEAT1 protects uremic toxin-induced intestinal epithelial barrier injury by regulating miR-122-5p/Occludin axis

Meng Han, Pathuama P, Jinhai Tian, Chen Wang, Shengnan Zhou, Lina Fu, Libin Wang, Na Tian

published 08 May 2025

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Fucoxanthin ameliorates Propionibacterium acnes-induced ear inflammation in mice by modulating the IκBα/NF-κB signaling pathway and inhibiting NF-κB nuclear translocation

Shan Jiang, Xiaoyan Peng, Yan Chen, Bingqi Dong, Hu Mao

published 07 May 2025

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Gene expression-based identification of prognostic markers in lung adenocarcinoma

Annette Salomonsson, Daniel Ehinger, Mats Jönsson, Johan Botling, Patrick Micke, Hans Brunnström, Johan Staaf, Maria Planck

published 07 May 2025

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Cardamonin suppresses mTORC1/SREBP1 through reducing Raptor and inhibits de novo lipogenesis in ovarian cancer

Peiguang Niu, Danyun Li, Huajiao Chen, Yanting Zhu, Jintuo Zhou, Jinhua Zhang, Ying Liu

published 02 May 2025

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PTPN21 inhibits cell apoptosis of acute lymphoblastic leukemia induced by chemotherapeutic agents via GADD45A and JNK signaling pathway

Chenze Zhao, Yu Zhang, Linlin Huang, Jingjing Xiang, Baodong Ye, Ni Zhu

published 30 Apr 2025

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DERL3 facilitates the progression of clear cell renal cell carcinoma by promoting epithelial-mesenchymal transition via regulation of the TGFB1 pathway

Chengtao Niu, Haodong Cui, Xintong Sun, Yuchang Yang, Xue Jiang, Zixiang Cong, Yiming Zhang, Zhihong Niu, Wei He

published 29 Apr 2025

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Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy

Chen Xue, Zhenxing Yan, Wenjing Cheng, Dong Zhang, Rong Zhang, Hongwei Duan, Lihong Zhang, Xiaofei Ma, Junjie Hu, Jian Kang, Xiaojun Ma

published 24 Apr 2025

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BnLPAT2 gene regulates oil accumulation in Brassica napus by modulating linoleic and linolenic acid levels in seeds

Luyao Huang, Zhiqiang Liao, Yujing Zou, Yong Liu, Huihui Wang, Leping Zou, Sun Liang, Shan Tong, Yu Kang, Tuo Chen, Xinghua Xiong, Man Xing

published 16 Apr 2025

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Engineering the green algae Chlamydomonas incerta for recombinant protein production

Kalisa Kang, Évellin do Espirito Santo, Crisandra Jade Diaz, Aaron Oliver, Lisa Saxton, Lauren May, Stephen Mayfield, João Vitor Dutra Molino

published 16 Apr 2025

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Trop-2 expression in non–small cell lung cancer

Peiwen Kuo, Emon Elboudwarej, Marianna Zavodovskaya, Kai-Wen Lin, Chingwei V. Lee, Lauri Diehl, Jilpa Patel, Sabeen Mekan, Juliane M. Jürgensmeier

published 15 Apr 2025

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