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Gene disruption

Adjuvant Effects Elicited by Novel Oligosaccharide Variants of Detoxified Meningococcal Lipopolysaccharides on Neisseria meningitidis Recombinant PorA Protein: A Comparison in Mice

Ojas H. Mehta, Gunnstein Norheim, J . Claire Hoe, Christine S. Rollier, Jerry C. Nagaputra, Katherine Makepeace, Muhammad Saleem, Hannah Chan, David J. P. Ferguson, Claire Jones, Manish Sadarangani, Derek W. Hood, Ian Feavers, Jeremy P. Derrick, Andrew J. Pollard, E . Richard Moxon

published 29 Dec 2014

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CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection

Weiming Wang, Chaobaihui Ye, Jingjing Liu, Di Zhang, Jason T. Kimata, Paul Zhou

published 26 Dec 2014

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Implications of Targeted Genomic Disruption of β-Catenin in BxPC-3 Pancreatic Adenocarcinoma Cells

Petter Angell Olsen, Nina Therese Solberg, Kaja Lund, Tore Vehus, Monika Gelazauskaite, Steven Ray Wilson, Stefan Krauss

published 23 Dec 2014

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The Circadian Clock Maintains Cardiac Function by Regulating Mitochondrial Metabolism in Mice

Akira Kohsaka, Partha Das, Izumi Hashimoto, Tomomi Nakao, Yoko Deguchi, Sabine S. Gouraud, Hidefumi Waki, Yasuteru Muragaki, Masanobu Maeda

published 12 Nov 2014

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Improved Genome Editing in Human Cell Lines Using the CRISPR Method

Ivan M. Munoz, Piotr Szyniarowski, Rachel Toth, John Rouse, Christophe Lachaud

published 10 Oct 2014

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The Telomerase Reverse Transcriptase Subunit from the Dimorphic Fungus Ustilago maydis

Dolores Bautista-España, Estela Anastacio-Marcelino, Guillermo Horta-Valerdi, Antonio Celestino-Montes, Milorad Kojic, Erasmo Negrete-Abascal, Hortensia Reyes-Cervantes, Candelario Vázquez-Cruz, Plinio Guzmán, Patricia Sánchez-Alonso

published 09 Oct 2014

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Characterizing the Roles of Cryphonectria parasitica RNA-Dependent RNA Polymerase-Like Genes in Antiviral Defense, Viral Recombination and Transposon Transcript Accumulation

Dong-Xiu Zhang, Martin J. Spiering, Donald L. Nuss

published 30 Sep 2014

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A High-Throughput Gene Disruption Methodology for the Entomopathogenic Fungus Metarhizium robertsii

Chuan Xu, Xing Zhang, Ying Qian, Xiaoxuan Chen, Ran Liu, Guohong Zeng, Hong Zhao, Weiguo Fang

published 15 Sep 2014

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Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues

Kwon Joo Yeo, Young-Soo Hong, Jun-Goo Jee, Jae Kyoung Lee, Hyo Jeong Kim, Jin-Wan Park, Eun-Hee Kim, Eunha Hwang, Sang-Yoon Kim, Eun-Gyeong Lee, Ohsuk Kwon, Hae-Kap Cheong

published 09 Sep 2014

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Function and Evolution of Two Forms of SecDF Homologs in Streptomyces coelicolor

Zhan Zhou, Yudong Li, Ning Sun, Zhihao Sun, Longxian Lv, Yufeng Wang, Libing Shen, Yong-Quan Li

published 20 Aug 2014

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Novel Lysophospholipid Acyltransferase PLAT1 of Aurantiochytrium limacinum F26-b Responsible for Generation of Palmitate-Docosahexaenoate-Phosphatidylcholine and Phosphatidylethanolamine

Eriko Abe, Kazutaka Ikeda, Eri Nutahara, Masahiro Hayashi, Atsushi Yamashita, Ryo Taguchi, Kosaku Doi, Daiske Honda, Nozomu Okino, Makoto Ito

published 04 Aug 2014

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Identification of the Genes That Contribute to Lactate Utilization in Helicobacter pylori

Shun Iwatani, Hiroyuki Nagashima, Rita Reddy, Seiji Shiota, David Y. Graham, Yoshio Yamaoka

published 31 Jul 2014

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New Clox Systems for Rapid and Efficient Gene Disruption in Candida albicans

Shahida Shahana, Delma S. Childers, Elizabeth R. Ballou, Iryna Bohovych, Frank C. Odds, Neil A. R. Gow, Alistair J. P. Brown

published 18 Jun 2014

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