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Fluorescence polarization

A highly-sensitive high throughput assay for dynamin's basal GTPase activity

Aparna Mohanakrishnan, Triet Vincent M. Tran, [ ... ], Sandra L. Schmid

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

Justin Hall, Amy Brault, [ ... ], Karen Leach

Directed evolution provides insight into conformational substrate sampling by SrtA

Muna Suliman, Vishaka Santosh, [ ... ], William A. Barton

Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells

Gunhild Sommer, Alena Fedarovich, [ ... ], Tilman Heise

Biochemical and biophysical investigations of the interaction between human glucokinase and pro-apoptotic BAD

Alix Rexford, Diego A. R. Zorio, Brian G. Miller

The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions

Hossein Nakhaeizadeh, Ehsan Amin, [ ... ], Mohammad Reza Ahmadian

High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion

Hiromi Shiratori, Carmen Feinweber, [ ... ], Eduard Resch

α-Mangostin Extraction from the Native Mangosteen (Garcinia mangostana L.) and the Binding Mechanisms of α-Mangostin to HSA or TRF

Ming Guo, Xiaomeng Wang, [ ... ], Peter E. Brodelius

A Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping Enzyme

Kristen M. Bullard-Feibelman, Benjamin P. Fuller, Brian J. Geiss

Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target

Katharine S. Dobb, Sarah J. Kaye, [ ... ], Jason D. Oliver

Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition

Lindsay E. Evans, Matthew D. Cheeseman, Norhakim Yahya, Keith Jones

Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

Zhonghua Wang, Akash Bhattacharya, Dmitri N. Ivanov

High-Throughput Screening for Ligands of the HEPN Domain of Sacsin

Xinlu Li, Marie Ménade, [ ... ], Kalle Gehring

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