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Fluorescence imaging

Synergistic effects of notoginsenoside R1 and saikosaponin B2 in atherosclerosis: A novel approach targeting PI3K/AKT/mTOR pathway and macrophage autophagy

Yihua Wang, Qing Liao, Xue Mei, Han Xu, Lijun Luo, Rong Huang, Yue Tang, Chunyang Zhou

published 27 Jun 2025

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Establishment of Cre/LoxP-mediated multifunctional reporter knock-in rats with the CRISPR system

Katsuyuki Nakamura, Sara Ito, Yoshihiro Ohguchi, Toshie Jimbo, Yusaku Wada, Ryota Nakajima, Masanobu Kanou, Kei Yamana, Hiroshi Ueda

published 25 Jun 2025

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Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines

Spencer C. Wei, Aaron J. Cantor, Jack Walleshauser, Rina Mepani, Kory Melton, Ashil Bans, Prachi Khekare, Suhani Gupta, Jonathan Wang, Craig Soares, Radwan Kiwan, Jieun Lee, Shannon McCawley, Vihasi Jani, Weng In Leong, Pawan K. Shahi, Jean Chan, Pierre Boivin, Peter Otoupal, Bikash R. Pattnaik, David M. Gamm, Krishanu Saha, Benjamin G. Gowen, Mary Haak-Frendscho, Mary J. Janatpour, Adam P. Silverman

published 24 Jun 2025

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Systematic review of generative adversarial networks (GANs) in cell microscopy: Trends, practices, and impact on image augmentation

Duway Nicolas Lesmes-Leon, Andreas Dengel, Sheraz Ahmed

published 24 Jun 2025

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Estimating the relative rates of lipopolysaccharide synthesis in Escherichia coli K-12 by click chemistry-mediated labeling

Sheng Shu, Wei Mi

published 23 Jun 2025

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Efficient endogenous protein labelling in Dictyostelium using CRISPR/Cas9 knock-in and split fluorescent proteins

Kensuke Yamashita, Tetsuya Muramoto

published 20 Jun 2025

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Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference

Johannes C. J. Heyn, Miguel Atienza Juanatey, Martin Falcke, Joachim O. Rädler

published 18 Jun 2025

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Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms

Jerald Tan, Chutipong Chiamkunakorn, Kanpapat Boonchuay, Yiying Shi, Bart P. Braeckman, Wichit Suthammarak

published 16 Jun 2025

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Marine fishes exhibit exceptional variation in biofluorescent emission spectra

Emily M. Carr, Mason A. Thurman, Rene P. Martin, Tate S. Sparks, John S. Sparks

published 16 Jun 2025

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Fast photostable expansion microscopy using QDots and deconvolution

Loku Gunawardhana, Wilna Moree, Jiaming Guo, Camille Artur, Tasha Womack, Jason L. Eriksen, David Mayerich

published 13 Jun 2025

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Development of an H&E on-block staining technique for collagen detection in cryo-fluorescence tomography imaging of frozen breast tissue samples

Erin P. Snoddy, Tien T. Tang, Natalie Fowlkes, Thomas Huynh, Kari J. Brewer Savannah, Alejandro Contreras, Gregory Reece, Kristy K. Brock

published 09 Jun 2025

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Generation and characterization of BAC transgenic mouse lines expressing a fluorescent protein in trigeminal and dorsal root ganglion neurons

Piu Banerjee, Takuya Sato, Takuji Iwasato

published 06 Jun 2025

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Measuring alignment of structural proteins in engineered tissue constructs using polarized Raman spectroscopy

Maedeh Lotfi, Hui Zhou, Janny Piñeiro Llanes, Ghatu Subhash, Chelsey S. Simmons, Malisa Sarntinoranont

published 30 May 2025

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