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Fibrosis

Understanding the action of bamocaftor as a potential drug candidate against Cystic Fibrosis Transmembrane Regulator protein: A computational approach

Naisarg Patel, Samrat Sarkar, Bala Murali V M, Ishan Kashyap, Premkumar Thiruselvam, Vino Sundararajan, Sajitha Lulu Sudhakaran

published 23 Jul 2025

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Magnetic resonance evaluation of three-dimensional liver fat fraction by hepatitis C status and associations with inflammatory cytokines

Jessie Torgersen, Craig W. Newcomb, Dean M. Carbonari, Shanae M. Smith, Katherine L. Brecker, Chamith S. Rajapakse, Brandon C. Jones, Christiana Cottrell, Rasleen Grewal, Jennifer C. Price, Joshua F. Baker, Jay R. Kostman, Stacey Trooskin, Rebecca A. Hubbard, Babette S. Zemel, Mary B. Leonard, Vincent Lo Re III

published 23 Jul 2025

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Vericiguat reduces atrial fibrillation recurrence by alleviating myocardial fibrosis via the TGF-β1/Smad2/3 pathway

XiaoLin Sun, Yawen Sheng, Pei Xu, Qian Peng, Zhongbao Ruan

published 18 Jul 2025

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Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD

Jongseong Ahn, Soyeon Kim, Jae Yoon Jeong, Sunghoon Heo, Kyung-hee Pyo, Eun-Ae Shin, Wonsik Kim, Jae-Ho Lee, Na Ryung Choi, Han Ah Lee, Hwang-Phill Kim, Sang-Hyun Song, Hwi Young Kim, Tae-You Kim, Jung Weon Lee

published 17 Jul 2025

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Targeting interferon-stimulated gene of 20 kDa protein (Isg20) inhibits ribosome biogenesis to ameliorate the progression of renal fibrosis

Xiaoming Liu, Huijuan Wang, Kai Wang, Ying Liu

published 07 Jul 2025

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Cardiometabolic dysfunction burden and mortality outcomes in metabolic dysfunction-associated steatotic liver disease

Ying Wen, Yu Min, Yi Lei, Zhigong Wei

published 03 Jul 2025

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A practical and safer model of nitrogen mustard injury in cornea

Ana M. Sandoval-Castellanos, Yao Ke, Tiffany M. Dam, Emanual Michael Maverakis, Mark J. Mannis, Xiao-Jing Wang, Min Zhao

published 03 Jul 2025

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Galectin-3 inhibition ameliorates hepatic steatosis in a multilineage 3D spheroid model

Francesca Sedda, Andrea Caddeo, Kavitha Sasidharan, Giovanni Perra, Rajesh Pal, Nicola Lai, Marta Anna Kowalik, Andrea Perra

published 03 Jul 2025

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Astragaloside IV combined with quercetin attenuates silica-induced pulmonary fibrosis by promoting autophagy and suppressing pyroptosis

Wenwen Zhu, Ningxia Zhao, Yinghua Ma, Wei Zhang, Jiazi Ma, Mao Cao, Yong Yang, Shichao Sun, Zhifeng Pan, Hua Shao, Zhongjun Du

published 25 Jun 2025

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Improved swin transformer-based thorax disease classification with optimal feature selection using chest X-ray

Nadim Rana, Yahaya Coulibaly, Ayman Noor, Talal H. Noor, Md Imran Alam, Zeba Khan, Ali Tahir, Mohammad Zubair Khan

published 25 Jun 2025

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Evaluation of the prevalence of MASLD, MASH and liver fibrosis in a Dutch bariatric cohort

Willy Theel, Willem-Pieter Brouwer, Elisabeth van Rossum, Jan Apers, Susan ter Borg, Tessa Noordermeer, Manuel Castro Cabezas

published 24 Jun 2025

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Thoracic magnetic resonance imaging in non-tuberculous mycobacterial pulmonary disease: Characteristics and potential implementation

Ieuan Edward Shepherd Evans, Timothy Baird, Charles S. Haworth, Christopher Johnson, Helen Barker, Uta Hill, Dorothy Grogono, Odiri Eneje, Nicholas Screaton, Andres Floto

published 23 Jun 2025

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Circulating exosome-circRNAs mediated downregulation of FGF9 through ceRNA mechanism aggravates renal fibrosis in diabetic nephropathy

Donglin Yang, Rongjiang Yin, Xiaomin Zhang, Xiaohui Wang, Xiaobin Pei, Zijie Guo, Pengyue Qiao, Kehan Zhu, Lin Wang, Pengchao Du

published 17 Jun 2025

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