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Fibroblasts

Age-dependent regulation of ELP1 exon 20 splicing in Familial Dysautonomia by RNA Polymerase II kinetics and chromatin structure

Federico Riccardi, Giulia Romano, Danilo Licastro, Franco Pagani

published 03 Jun 2024

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The HOCl dry fog–is it safe for human cells?

Rafał Bogdan Lewandowski, Małgorzata Stępińska, Łukasz Osuchowski, Wiktoria Kasprzycka, Monika Dobrzyńska, Zygmunt Mierczyk, Elżbieta Anna Trafny

published 29 May 2024

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Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I

Elena Cubero, Ana Ruano, Aida Delgado, Xavier Barril, Sara Morales, Ana Trapero, Lorenzo Leoni, Manolo Bellotto, Roberto Maj, Beatriz Calvo-Flores Guzmán, Natalia Pérez-Carmona, Ana Maria Garcia-Collazo

published 20 May 2024

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The effect of TG2-inhibitory monoclonal antibody zampilimab on tissue fibrosis in human in vitro and primate in vivo models of chronic kidney disease

Linghong Huang, Helene Bon, Mabrouka Maamra, Toby Holmes, John Atkinson, Katharine Cain, Jeff Kennedy, Catherine Kettleborough, David Matthews, Breda Twomey, Jia Ni, Zhizhan Song, Philip F. Watson, Timothy S. Johnson

published 16 May 2024

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Inhibitory effect of doxycycline conjugated with deoxycholic acid and polyethylenimine conjugate on nasal fibroblast differentiation and extracellular production

Jae-Min Shin, Hyun-Woo Yang, Su-yeon Lim, Ji-hoon Jeong, Il-Ho Park

published 16 May 2024

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Epithelial-mesenchymal interaction protects normal colonocytes from 4-HNE-induced phenotypic transformation

Jacques Dupuy, Emma Cogo, Edwin Fouché, Françoise Guéraud, Fabrice Pierre, Pascale Plaisancié

published 26 Apr 2024

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An orchestra of machine learning methods reveals landmarks in single-cell data exemplified with aging fibroblasts

Lauritz Rasbach, Aylin Caliskan, Fatemeh Saderi, Thomas Dandekar, Tim Breitenbach

published 17 Apr 2024

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Elevated interleukin-8 expression by skin fibroblasts as a potential contributor to pain in women with Fabry disease

Lukas Hofmann, Julia Grüner, Katharina Klug, Maximilian Breyer, Thomas Klein, Vanessa Hochheimer, Laura Wagenhäuser, Erhard Wischmeyer, Nurcan Üçeyler

published 09 Apr 2024

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Quantitative imaging and semiotic phenotyping of mitochondrial network morphology in live human cells

Sophie Charrasse, Victor Racine, Charlotte Saint-Omer, Titouan Poquillon, Loïc Lionnard, Marine Ledru, Christophe Gonindard, Sandrine Delaunois, Karima Kissa, Richard E. Frye, Manuela Pastore, Christelle Reynes, Mathilde Frechet, Hanane Chajra, Abdel Aouacheria

published 28 Mar 2024

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Single-cell analysis reveals landscape of endometrial cancer response to estrogen and identification of early diagnostic markers

Chunli Dong, Liyan Zhao, Xiongtao Liu, Ling Dang, Xin Zhang

published 22 Mar 2024

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Chromolaena odorata layered-nitrile rubber polymer transdermal patch enhanced wound healing in vivo

Mazlyzam Abdul Latif, Asrul Mustafa, Lee Chee Keong, Asmah Hamid

published 11 Mar 2024

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Serum levels of matrix metalloproteinases 1, 2, and 7, and their tissue inhibitors 1, 2, 3, and 4 in polytraumatized patients: Time trajectories, correlations, and their ability to predict mortality

Lukas L. Negrin, Greta L. Carlin, Robin Ristl, Stefan Hajdu

published 08 Mar 2024

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A xenotransplantation mouse model to study physiology of the mammary gland from large mammals

James L. Miller, Alexandra Reddy, Rebecca M. Harman, Gerlinde R. Van de Walle

published 28 Feb 2024

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