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Fibroblasts

NOTCH1 promotes the elevation of GM-CSF and IL-6 through the EZH2/STAT3 pathway to facilitate the fibrotic state of the myocardium in DLBCL

Huimin Zhang, Wen Dong, Lihong Zhang, Bing Ma, Jianying Wang, Yang Shen, Dan Zhao, Wanyi Yin, Yuexian Li, Qingchi Liu

published 14 Feb 2025

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4-Hydroxy-2-nonenal causes nuclear accumulation of p62 by inhibiting Xpo1 and promoting the proteolytic pathway in the nucleus

Emi Kayama, Ning Baoshuo, Rinna Tatsuno, Kanako Nishi, Elsayed S. I. Mohammed, Yumi Abiko, Toru Yanagawa, Satoru Takahashi, Eiji Warabi

published 03 Feb 2025

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In vitro cytotoxicity (irritant potency) of toothpaste ingredients

Shaira R. Kasi, Sanne Roffel, Mutlu Özcan, Susan Gibbs, Albert J. Feilzer

published 30 Jan 2025

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The cellular response of lipopolysaccharide-induced inflammation in keratoconus human corneal fibroblasts to RB-PDT: Insights into cytokines, chemokines and related signaling pathways

Ning Chai, Tanja Stachon, Sabrina Häcker, Tim Berger, Zhen Li, Maryam Amini, Shweta Suiwal, Berthold Seitz, Achim Langenbucher, Nóra Szentmáry

published 27 Jan 2025

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mGBP2 engages Galectin-9 for immunity against Toxoplasma gondii

Elisabeth Kravets, Gereon Poschmann, Sebastian Hänsch, Veronica Raba, Stefanie Weidtkamp-Peters, Daniel Degrandi, Kai Stühler, Klaus Pfeffer

published 24 Jan 2025

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Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models

Yixing Wu, Karen Cleverley, Frances K. Wiseman

published 22 Jan 2025

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Nucleosome repositioning in cardiac reprogramming

Sonalí Harris, Syeda S. Baksh, Xinghua Wang, Iqra Anwar, Richard E. Pratt, Victor J. Dzau, Conrad P. Hodgkinson

published 15 Jan 2025

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Aligned membranes regulate wound healing via MMP12 secreted by macrophages

Hongli Ma, Limin Gong, Xi Yang, Hui Fang, Jiacai He, Chenbing Wang

published 15 Jan 2025

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In vitro and in vivo evaluation of Ulva lactuca for wound healing

Chien-Hsing Wang, Zih-Ting Huang, Kuo-Feng Tai

published 08 Jan 2025

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Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways

Binmei Zhang, Jingxiu Hou, Jiaren Liu, Junhui He, Yunan Gao, Guangnan Li, Tianjiao Ma, Xin Lv, Li Dong, Wei Yang

published 08 Jan 2025

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Cyclosporine A causes gingival overgrowth via reduced G₁ cell cycle arrest in gingival fibroblasts

Reiri Takeuchi, Takatoshi Nomura, Manabu Yaguchi, Noriko Kuwahara, Yuta Amino, Chieko Taguchi, Itaru Suzuki, Haruka Suzuki, Teruaki Nagashima, Kazumune Arikawa, Yuichiro Okada, Takato Nomoto, Koichi Hiratsuka

published 20 Dec 2024

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Linsitinib inhibits IGF-1-induced cell proliferation and hyaluronic acid secretion by suppressing PI3K/Akt and ERK pathway in orbital fibroblasts from patients with thyroid-associated ophthalmopathy

Ji-Young Lee, Seong-Beom Lee, Suk-Woo Yang, Ji-Sun Paik

published 18 Dec 2024

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Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis

Albrecht Meyer zu Schwabedissen, Silvia Vergarajauregui, Marko Bertog, Kerstin Amann, Felix B. Engel, Christoph Daniel

published 05 Dec 2024

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