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Fibroblast growth factor

In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

Diogo Gonçalves, Guylène Rignol, Pierre Dellugat, Guido Hartmann, Stephanie Sarrazy Garcia, Jeffrey Stavenhagen, Luca Santarelli, Elvire Gouze, Christian Czech

published 28 Dec 2020

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Fibroblast growth factor 23 and cognitive impairment: The health, aging, and body composition study

David A. Drew, Ronit Katz, Stephen Kritchevsky, Joachim H. Ix, Michael Shlipak, Anne B. Newman, Andy Hoofnagle, Linda Fried, Orlando M. Gutiérrez, Mark Sarnak

published 11 Dec 2020

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TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness

Tomoyo Matsumura, Tomokazu Fujimoto, Akiko Futakuchi, Yuji Takihara, Fumika Watanabe-Kitamura, Eri Takahashi, Miyuki Inoue-Mochita, Hidenobu Tanihara, Toshihiro Inoue

published 18 Nov 2020

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Fgf10-CRISPR mosaic mutants demonstrate the gene dose-related loss of the accessory lobe and decrease in the number of alveolar type 2 epithelial cells in mouse lung

Munenori Habuta, Akihiro Yasue, Ken-ichi T. Suzuki, Hirofumi Fujita, Keita Sato, Hitomi Kono, Ayuko Takayama, Tetsuya Bando, Satoru Miyaishi, Seiichi Oyadomari, Eiji Tanaka, Hideyo Ohuchi

published 15 Oct 2020

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The effect of hydration status on plasma FGF21 concentrations in humans: A subanalysis of a randomised crossover trial

Harriet A. Carroll, Yung-Chih Chen, Iain Templeman, Lewis J. James, James A. Betts, William V. Trim

published 05 Aug 2020

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Mediation of the relationship between proteinuria and serum phosphate: Insight from the KNOW-CKD study

Ji Yong Jung, Han Ro, Jae Hyun Chang, Ae Jin Kim, Hyun Hee Lee, Seung Hyeok Han, Tae-Hyun Yoo, Kyu-Beck Lee, Yeong Hoon Kim, Soo Wan Kim, Sue Kyung Park, Dong-Wan Chae, Kook-Hwan Oh, Curie Ahn, Wookyung Chung

published 22 Jun 2020

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PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells

Chuchu Qiao, Hongyan Qian, Jue Wang, Tingting Zhao, Pengyu Ma, Sicen Wang, Tao Zhang, Xinshe Liu

published 18 Jun 2020

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Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2^C342Y/+ mouse models of Crouzon syndrome

Hwa Kyung Nam, Iva Vesela, Sara Dean Schutte, Nan E. Hatch

published 29 May 2020

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Investigating the epithelial barrier and immune signatures in the pathogenesis of equine insect bite hypersensitivity

Iva Cvitas, Simone Oberhänsli, Tosso Leeb, Martina Dettwiler, Eliane Müller, Remy Bruggman, Eliane Isabelle Marti

published 28 Apr 2020

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Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1

Kazuhiro Kuga, Yoichiro Kusakari, Ken Uesugi, Kentaro Semba, Takashi Urashima, Toru Akaike, Susumu Minamisawa

published 21 Apr 2020

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INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

Phillip C. C. Liu, Holly Koblish, Liangxing Wu, Kevin Bowman, Sharon Diamond, Darlise DiMatteo, Yue Zhang, Michael Hansbury, Mark Rupar, Xiaoming Wen, Paul Collier, Patricia Feldman, Ronald Klabe, Krista A. Burke, Maxim Soloviev, Christine Gardiner, Xin He, Alla Volgina, Maryanne Covington, Bruce Ruggeri, Richard Wynn, Timothy C. Burn, Peggy Scherle, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Gregory Hollis

published 21 Apr 2020

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Pharmacokinetics and safety after once and twice a day doses of meclizine hydrochloride administered to children with achondroplasia

Hiroshi Kitoh, Masaki Matsushita, Kenichi Mishima, Tadashi Nagata, Yasunari Kamiya, Kohei Ueda, Yachiyo Kuwatsuka, Hiroshi Morikawa, Yasuhiro Nakai, Naoki Ishiguro

published 13 Apr 2020

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The interoceptive hippocampus: Mouse brain endocrine receptor expression highlights a dentate gyrus (DG)–cornu ammonis (CA) challenge–sufficiency axis

Richard Lathe, Sheena Singadia, Crispin Jordan, Gernot Riedel

published 15 Jan 2020

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