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Epigenetics

Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine

Aaron Shaykevich, Danbee Chae, Isaac Silverman, Sanjay Goel, Radhashree Maitra

published 17 Jun 2025

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Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms

Jerald Tan, Chutipong Chiamkunakorn, Kanpapat Boonchuay, Yiying Shi, Bart P. Braeckman, Wichit Suthammarak

published 16 Jun 2025

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SERS-based detection of DNA methylation for cancer diagnosis: Cation-mediated adsorption to silver nanoparticles

Stefania D. Iancu, Vlad Moisoiu, Bogdan Adrian Tigu, Andrei Stefancu, Oana M. Biro, Ciprian Tomuleasa, Nicolae Leopold

published 13 Jun 2025

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Identification and characterization of eccDNA-driven genes in humans

Yuxi Gu, Yidan Song, Jun Liu

published 06 Jun 2025

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Epigenetic responses in Borrelia-infected Ixodes scapularis ticks: Over-expression of euchromatic histone lysine methyltransferase 2 and no change in DNA methylation

Grace Hadley MacIntosh, Alexandra C. Nuyens, Jessica L. Vickery, Anne Berthold, Vett K. Lloyd

published 05 Jun 2025

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Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of attention deficit-hyperactivity disorder

Rodrigo Vidal, Ignacio Lopez, Gonzalo Ugarte, Darwin Contreras, Ricardo Piña, Felipe Godoy, Carlos Rozas, David Rubio, Carola Mantellero, Luis Constandil, Jorge Escobar, Bernardo Morales

published 04 Jun 2025

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AD-GCN: A novel graph convolutional network integrating multi-omics data for enhanced Alzheimer’s disease diagnosis

Zilu Li, Qingyun Li, Xiaoqing Li, Wei Luo, Haiyan Guo, Chunyan Zhao, Canzhen Yang, Anke Xie, Kai Hu, Yangfan Guo

published 02 Jun 2025

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Epimedin C enhances mitochondrial energy supply by regulating the interaction between MIC25 and UBC in rodent model

Mi Huang, Lei Yu, Zhong Li, Ying Wang, Chunlin Yang

published 28 May 2025

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Integrative analysis of epigenetic subtypes in acute myeloid Leukemia: A multi-center study combining machine learning for prognostic and therapeutic insights

Jincan Li, Shengyue Wang

published 28 May 2025

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Epigenetic regulation of individual components of combined hepatocellular-cholangiocarcinoma

Kyle M. Schachtschneider, Luke N. Redlon, Ryan Peter Lokken, Yu-Hui Huang, Grace Guzman, Lawrence B. Schook, Ron C. Gaba

published 27 May 2025

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Identification of maternal allele sequences of IG-DMR that are essential for neonatal viability

Satoshi Hara, Akari Muramatsu, Miho Terao, Shuji Takada

published 22 May 2025

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Epigenetic assessments of alcohol consumption predict mortality in smokers at risk for lung cancer in the prostate, lung, colorectal and ovarian cancer screening trial

Robert Philibert, Steven R.H. Beach, James A. Mills, Kelsey Dawes, Richard M. Hoffman, Jessica C. Sieren, Ellyse M. Froehlich, Kaitlyn M. deBlois, Jeffrey D. Long

published 22 May 2025

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Bisulphite sequencing in the presence of cytosine-conversion errors

Thomas James Ellis, Viktoria Nizhynska, Rahul Pisupati, Almudena Mollá-Morales, Magnus Nordborg

published 21 May 2025

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