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Epigenetics

Nucleases as a barrier to gene silencing in the cotton boll weevil, Anthonomus grandis

Rayssa Almeida Garcia, Leonardo Lima Pepino Macedo, Danila Cabral do Nascimento, François-Xavier Gillet, Clidia Eduarda Moreira-Pinto, Muhammad Faheem, Angelina Maria Moreschi Basso, Maria Cristina Mattar Silva, Maria Fatima Grossi-de-Sa

published 20 Dec 2017

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Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects

Roy Eldor, Luke Norton, Marcel Fourcaudot, Cynthia Galindo, Ralph A. DeFronzo, Muhammad Abdul-Ghani

published 20 Dec 2017

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Tumor suppressor protein p53-mediated repression of human mitotic centromere-associated kinesin gene expression is exerted via down-regulation of Sp1 level

Do Youn Jun, Ji Young Lee, Hae Sun Park, Yun Han Lee, Young Ho Kim

published 15 Dec 2017

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High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanoma

Haiming Xu, Jingwen Gong, Hui Liu

published 15 Dec 2017

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Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei

Michael E. Steinmann, Remo S. Schmidt, Juan P. Macêdo, Christina Kunz Renggli, Peter Bütikofer, Doris Rentsch, Pascal Mäser, Erwin Sigel

published 15 Dec 2017

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BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9⁺ leukemic cells

Marco Carretta, Annet Z. Brouwers-Vos, Matthieu Bosman, Sarah J. Horton, Joost H. A. Martens, Edo Vellenga, Jan Jacob Schuringa

published 14 Dec 2017

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Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes

Martha Scott Tomlinson, Paige A. Bommarito, Elizabeth M. Martin, Lisa Smeester, Raina N. Fichorova, Andrew B. Onderdonk, Karl C. K. Kuban, T. Michael O’Shea, Rebecca C. Fry

published 14 Dec 2017

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Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis

Bhairab N. Singh, Naoyuki Tahara, Yasuhiko Kawakami, Satyabrata Das, Naoko Koyano-Nakagawa, Wuming Gong, Mary G. Garry, Daniel J. Garry

published 12 Dec 2017

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Attenuated expression of MTR in both prenatally androgenized mice and women with the hyperandrogenic phenotype of PCOS

Lei Lei, Lijun Ding, Jing Su, Mengyuan Liu, Qingqing Shi, Jianjun Zhou, Haixiang Sun, Guijun Yan

published 12 Dec 2017

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Consequences of supplying methyl donors during pregnancy on the methylome of the offspring from lactating and non-lactating dairy cattle

Alex Bach, Anna Aris, Isabel Guasch

published 11 Dec 2017

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A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure

Christina Y. Hung, Barbara Volkmar, James D. Baker, Johann W. Bauer, Emanuela Gussoni, Stefan Hainzl, Alfred Klausegger, Jose Lorenzo, Ivana Mihalek, Olaf Rittinger, Mustafa Tekin, Julia E. Dallman, Olaf A. Bodamer

published 11 Dec 2017

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Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes

Sandra Rodríguez-Rodero, Edelmiro Menéndez-Torre, Gustavo Fernández-Bayón, Paula Morales-Sánchez, Lourdes Sanz, Estrella Turienzo, Juan José González, Ceferino Martinez-Faedo, Lorena Suarez-Gutiérrez, Jessica Ares, Lucia Díaz-Naya, Alicia Martin-Nieto, Juan L. Fernández-Morera, Mario F. Fraga, Elías Delgado-Álvarez

published 11 Dec 2017

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DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird

Ricardo De Paoli-Iseppi, Andrea M. Polanowski, Clive McMahon, Bruce E. Deagle, Joanne L. Dickinson, Mark A. Hindell, Simon N. Jarman

published 07 Dec 2017

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