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Epigenetics

Rationale and study protocol of the MAMELI Cohort study (Mapping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a Living lab)

Valentina Bollati, Federica Rota, Laura Dioni, Chiara Favero, Simona Iodice, Marta Gallazzi, Andrea Spinazzè, Giacomo Fanti, Davide Campagnolo, Tiago Nardi, Davide Biganzoli, Eva Dariol, Rachele Matsagani, Mirjam Hoxha, Paola Monti, Benedetta Albetti, Letizia Tarantini, Davide Barbuto, Ester Luconi, Giuseppe Marano, Giacomo Biganzoli, Roberta Biciuffi, Patrizia Boracchi, Domenico M. Cavallo, Pilar M. Guerrieri, Fabio Mosca, Stefano Gustincich, Giovanni Sanesi, Luca Ferrari, Michele Carugno, Silvia Fustinoni, Angela Cecilia Pesatori, Luca Pandolfini, Michele Miragoli, Andrea Cattaneo, Elia Biganzoli

published 09 Jul 2025

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Quantifying conformational heterogeneity of 3D genome organization in fruit fly

Samira Mali, Igor S. Tolokh, Erik Cross, Alexey V. Onufriev

published 03 Jul 2025

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Neutrophil extracellular traposis in cancer patients with acute ischemic stroke

Jae-Won Hyun, Rosah May Palermo Payumo, Jieun Chung, You-Ri Kang, Su-Hyun Kim, Ho Jin Kim, Ji-Youn Han, Sang-Yoon Park

published 27 Jun 2025

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3Mont: A multi-omics integrative tool for breast cancer subtype stratification

Miray Unlu Yazici, J. S. Marron, Burcu Bakir-Gungor, Fei Zou, Malik Yousef

published 27 Jun 2025

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Aging dimensions and markers as relative predictors of mortality in a longitudinal epidemiological sample

Kristian E. Markon, Frank D. Mann, Colin D. Freilich, Steve Cole, Robert F. Krueger

published 18 Jun 2025

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Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine

Aaron Shaykevich, Danbee Chae, Isaac Silverman, Sanjay Goel, Radhashree Maitra

published 17 Jun 2025

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Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms

Jerald Tan, Chutipong Chiamkunakorn, Kanpapat Boonchuay, Yiying Shi, Bart P. Braeckman, Wichit Suthammarak

published 16 Jun 2025

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SERS-based detection of DNA methylation for cancer diagnosis: Cation-mediated adsorption to silver nanoparticles

Stefania D. Iancu, Vlad Moisoiu, Bogdan Adrian Tigu, Andrei Stefancu, Oana M. Biro, Ciprian Tomuleasa, Nicolae Leopold

published 13 Jun 2025

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Identification and characterization of eccDNA-driven genes in humans

Yuxi Gu, Yidan Song, Jun Liu

published 06 Jun 2025

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Epigenetic responses in Borrelia-infected Ixodes scapularis ticks: Over-expression of euchromatic histone lysine methyltransferase 2 and no change in DNA methylation

Grace Hadley MacIntosh, Alexandra C. Nuyens, Jessica L. Vickery, Anne Berthold, Vett K. Lloyd

published 05 Jun 2025

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Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of attention deficit-hyperactivity disorder

Rodrigo Vidal, Ignacio Lopez, Gonzalo Ugarte, Darwin Contreras, Ricardo Piña, Felipe Godoy, Carlos Rozas, David Rubio, Carola Mantellero, Luis Constandil, Jorge Escobar, Bernardo Morales

published 04 Jun 2025

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AD-GCN: A novel graph convolutional network integrating multi-omics data for enhanced Alzheimer’s disease diagnosis

Zilu Li, Qingyun Li, Xiaoqing Li, Wei Luo, Haiyan Guo, Chunyan Zhao, Canzhen Yang, Anke Xie, Kai Hu, Yangfan Guo

published 02 Jun 2025

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Epimedin C enhances mitochondrial energy supply by regulating the interaction between MIC25 and UBC in rodent model

Mi Huang, Lei Yu, Zhong Li, Ying Wang, Chunlin Yang

published 28 May 2025

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