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Epigenetics

All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus

Ling Lu, Jilin Ma, Zhiyuan Li, Qin Lan, Maogen Chen, Ya Liu, Zanxian Xia, Julie Wang, Yuanping Han, Wei Shi, Valerie Quesniaux, Bernhard Ryffel, David Brand, Bin Li, Zhongmin Liu, Song Guo Zheng

published 13 Sep 2011

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D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease

Soyeon Lim, Adrianne S. Chesser, Jonathan C. Grima, Phillip M. Rappold, David Blum, Serge Przedborski, Kim Tieu

published 12 Sep 2011

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Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase

Taito Nishino, Changshan Wang, Makiko Mochizuki-Kashio, Mitsujiro Osawa, Hiromitsu Nakauchi, Atsushi Iwama

published 12 Sep 2011

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Transcription Factor Binding Site Positioning in Yeast: Proximal Promoter Motifs Characterize TATA-Less Promoters

Ionas Erb, Erik van Nimwegen

published 09 Sep 2011

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DAF-16 and Δ⁹ Desaturase Genes Promote Cold Tolerance in Long-Lived Caenorhabditis elegans age-1 Mutants

Fiona R. Savory, Steven M. Sait, Ian A. Hope

published 08 Sep 2011

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In Vivo RNAi Screen Reveals Neddylation Genes as Novel Regulators of Hedgehog Signaling

Juan Du, Junzheng Zhang, Ying Su, Min Liu, Jason K. Ospina, Shengyuan Yang, Alan Jian Zhu

published 08 Sep 2011

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Zebrafish foxo3b Negatively Regulates Canonical Wnt Signaling to Affect Early Embryogenesis

Xun-wei Xie, Jing-Xia Liu, Bo Hu, Wuhan Xiao

published 07 Sep 2011

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Differential Methylation of the HPV 16 Upstream Regulatory Region during Epithelial Differentiation and Neoplastic Transformation

Svetlana Vinokurova, Magnus von Knebel Doeberitz

published 07 Sep 2011

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Kebab: Kinetochore and EB1 Associated Basic Protein That Dynamically Changes Its Localisation during Drosophila Mitosis

Ana M. Meireles, Nikola S. Dzhindzhev, Hiroyuki Ohkura

published 02 Sep 2011

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Phospholipase C Isozymes Are Deregulated in Colorectal Cancer – Insights Gained from Gene Set Enrichment Analysis of the Transcriptome

Stine A. Danielsen, Lina Cekaite, Trude H. Ågesen, Anita Sveen, Arild Nesbakken, Espen Thiis-Evensen, Rolf I. Skotheim, Guro E. Lind, Ragnhild A. Lothe

published 01 Sep 2011

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Targeting Epigenetic Regulation of miR-34a for Treatment of Pancreatic Cancer by Inhibition of Pancreatic Cancer Stem Cells

Dara Nalls, Su-Ni Tang, Marianna Rodova, Rakesh K. Srivastava, Sharmila Shankar

published 31 Aug 2011

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High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

Joost Schulte, Katharine J. Sepp, Chaohong Wu, Pengyu Hong, J. Troy Littleton

published 31 Aug 2011

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Testing the FMR1 Promoter for Mosaicism in DNA Methylation among CpG Sites, Strands, and Cells in FMR1-Expressing Males with Fragile X Syndrome

Reinhard Stöger, Diane P. Genereux, Randi J. Hagerman, Paul J. Hagerman, Flora Tassone, Charles D. Laird

published 31 Aug 2011

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