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Electron density

Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors

Cho Yeow Koh, Sundramurthy Kumar, Maria Kazimirova, Patricia A. Nuttall, Uvaraj P. Radhakrishnan, Seongcheol Kim, Pudur Jagadeeswaran, Takayuki Imamura, Jun Mizuguchi, Sadaaki Iwanaga, Kunchithapadam Swaminathan, R. Manjunatha Kini

published 28 Oct 2011

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Evidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase KdsB, an Enzyme Involved in Lipopolysaccharide Biosynthesis

Helgo Schmidt, Jeroen R. Mesters, Jing Wu, Ronald W. Woodard, Rolf Hilgenfeld, Uwe Mamat

published 03 Aug 2011

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The Crystal Structure of the Human Co-Chaperone P58^IPK

Maria Svärd, Ekaterina I. Biterova, Jean-Marie Bourhis, Jodie E. Guy

published 25 Jul 2011

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Structure of the Full-Length Major Pilin from Streptococcus pneumoniae: Implications for Isopeptide Bond Formation in Gram-Positive Bacterial Pili

Neil G. Paterson, Edward N. Baker

published 08 Jul 2011

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Calpain-Catalyzed Proteolysis of Human dUTPase Specifically Removes the Nuclear Localization Signal Peptide

Zoltán Bozóky, Gergely Róna, Éva Klement, Katalin F. Medzihradszky, Gábor Merényi, Beáta G. Vértessy, Peter Friedrich

published 19 May 2011

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Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin

Hiroki Tanaka, Terukazu Nogi, Norihisa Yasui, Kenji Iwasaki, Junichi Takagi

published 28 Apr 2011

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Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

Jeong Joo Kim, Darren E. Casteel, Gilbert Huang, Taek Hun Kwon, Ronnie Kuo Ren, Peter Zwart, Jeffrey J. Headd, Nicholas Gene Brown, Dar-Chone Chow, Timothy Palzkill, Choel Kim

published 19 Apr 2011

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Structural Asymmetry of Phosphodiesterase-9, Potential Protonation of a Glutamic Acid, and Role of the Invariant Glutamine

Jing Hou, Jie Xu, Ming Liu, Ruizhi Zhao, Hai-Bin Luo, Hengming Ke

published 31 Mar 2011

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Crystal Structure of a Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity

Avinash Gill, Thomas C. Scanlon, Daniel C. Osipovitch, Dean R. Madden, Karl E. Griswold

published 07 Mar 2011

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Structural Analysis of Alkaline β-Mannanase from Alkaliphilic Bacillus sp. N16-5: Implications for Adaptation to Alkaline Conditions

Yueju Zhao, Yunhua Zhang, Yang Cao, Jianxun Qi, Liangwei Mao, Yanfen Xue, Feng Gao, Hao Peng, Xiaowei Wang, George F. Gao, Yanhe Ma

published 28 Jan 2011

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Crystal Structure of UBA2^ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Jing Wang, Asad M. Taherbhoy, Harold W. Hunt, Steven N. Seyedin, David W. Miller, Darcie J. Miller, Danny T. Huang, Brenda A. Schulman

published 30 Dec 2010

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The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights

Yoshiteru Sato, Nick Ramalanjaona, Tiphaine Huet, Noelle Potier, Judit Osz, Pierre Antony, Carole Peluso-Iltis, Pierre Poussin-Courmontagne, Eric Ennifar, Yves Mély, Annick Dejaegere, Dino Moras, Natacha Rochel

published 30 Nov 2010

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Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis

Charles W. Pemble IV, Perdeep K. Mehta, Smriti Mehra, Zhenmei Li, Amanda Nourse, Richard E. Lee, Stephen W. White

published 30 Nov 2010

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