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Electron density

Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors

Cho Yeow Koh, Sundramurthy Kumar, [ ... ], R. Manjunatha Kini

Evidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase KdsB, an Enzyme Involved in Lipopolysaccharide Biosynthesis

Helgo Schmidt, Jeroen R. Mesters, [ ... ], Uwe Mamat

The Crystal Structure of the Human Co-Chaperone P58^IPK

Maria Svärd, Ekaterina I. Biterova, Jean-Marie Bourhis, Jodie E. Guy

Structure of the Full-Length Major Pilin from Streptococcus pneumoniae: Implications for Isopeptide Bond Formation in Gram-Positive Bacterial Pili

Neil G. Paterson, Edward N. Baker

Calpain-Catalyzed Proteolysis of Human dUTPase Specifically Removes the Nuclear Localization Signal Peptide

Zoltán Bozóky, Gergely Róna, [ ... ], Peter Friedrich

Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin

Hiroki Tanaka, Terukazu Nogi, [ ... ], Junichi Takagi

Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

Jeong Joo Kim, Darren E. Casteel, [ ... ], Choel Kim

Structural Asymmetry of Phosphodiesterase-9, Potential Protonation of a Glutamic Acid, and Role of the Invariant Glutamine

Jing Hou, Jie Xu, [ ... ], Hengming Ke

Crystal Structure of a Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity

Avinash Gill, Thomas C. Scanlon, [ ... ], Karl E. Griswold

Structural Analysis of Alkaline β-Mannanase from Alkaliphilic Bacillus sp. N16-5: Implications for Adaptation to Alkaline Conditions

Yueju Zhao, Yunhua Zhang, [ ... ], Yanhe Ma

Crystal Structure of UBA2^ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Jing Wang, Asad M. Taherbhoy, [ ... ], Brenda A. Schulman

The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights

Yoshiteru Sato, Nick Ramalanjaona, [ ... ], Natacha Rochel

Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis

Charles W. Pemble IV, Perdeep K. Mehta, [ ... ], Stephen W. White

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