Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Drug design

Whole genome sequencing and rare variant analysis in essential tremor families

Zagaa Odgerel, Shilpa Sonti, [ ... ], Lorraine N. Clark

Identification of putative pathogenic single nucleotide variants (SNVs) in genes associated with heart disease in 290 cases of stillbirth

Ellika Sahlin, Anna Gréen, [ ... ], Erik Iwarsson

Rare, potentially pathogenic variants in 21 keratoconus candidate genes are not enriched in cases in a large Australian cohort of European descent

Sionne E. M. Lucas, Tiger Zhou, [ ... ], Kathryn P. Burdon

Generalising better: Applying deep learning to integrate deleteriousness prediction scores for whole-exome SNV studies

Ilia Korvigo, Andrey Afanasyev, Nikolay Romashchenko, Mikhail Skoblov

Overall survival in EGFR mutated non-small-cell lung cancer patients treated with afatinib after EGFR TKI and resistant mechanisms upon disease progression

A. J. van der Wekken, J. L. Kuiper, [ ... ], H. J. M. Groen

Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy

Rita Mendes de Almeida, Joana Tavares, [ ... ], Luís Rocha Lopes

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

Ulrike Esslinger, Sophie Garnier, [ ... ], Eric Villard

The Open Form Inducer Approach for Structure-Based Drug Design

Daniel Ken Inaoka, Maiko Iida, [ ... ], Shigeharu Harada

Hydrogen Bond Dynamic Propensity Studies for Protein Binding and Drug Design

Cintia A. Menéndez, Sebastián R. Accordino, Darío C. Gerbino, Gustavo A. Appignanesi

Incorporating Non-Coding Annotations into Rare Variant Analysis

Tom G. Richardson, Colin Campbell, Nicholas J Timpson, Tom R. Gaunt

A Protein Domain and Family Based Approach to Rare Variant Association Analysis

Tom G. Richardson, Hashem A. Shihab, [ ... ], Tom R. Gaunt

In-Silico Analysis of Inflammatory Bowel Disease (IBD) GWAS Loci to Novel Connections

Md. Mesbah-Uddin, Ramu Elango, [ ... ], Fahad A. Al-Abbasi

Evidence for Evolutionary and Nonevolutionary Forces Shaping the Distribution of Human Genetic Variants near Transcription Start Sites

Giovanni Scala, Ornella Affinito, [ ... ], Sergio Cocozza

Advertisement

Create a weekly email alert for: Drug design

You can change these options by clicking profile then "Alerts and Notifications"