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Drug absorption

Exploration of Type III effector Xanthomonas outer protein Q (XopQ) inhibitor from Picrasma quassioides as an antibacterial agent using chemoinformatics analysis

Prasanna D. Revanasiddappa, H. G. Gowtham, Chikkanna G. S., Suchithra Gangadhar, Satish A., M. Murali, Chandan Shivamallu, Raghu Ram Achar, Ekaterina Silina, Victor Stupin, Natalia Manturova, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Shiva Prasad Kollur, Kestur Nagaraj Amruthesh

published 18 Jun 2024

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Enhancing drug therapy in ostomy patients: Best practice recommendations for medication management

Vivien Berger, Matthias Reeh, Martin Scherer, Steffen Härterich, Sven Möller, Eva-Maria Anette Wansing, Annika van der Linde, Claudia Langebrake

published 06 Jun 2024

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Solid dispersion systems for enhanced dissolution of poorly water-soluble candesartan cilexetil: In vitro evaluation and simulated pharmacokinetics studies

Israa Saad Mustafa Ali, Uday Aziz Sajad, Bazigha K. Abdul Rasool

published 06 Jun 2024

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Mathematical modeling of transdermal delivery of topical drug formulations in a dynamic microfluidic diffusion chamber in health and disease

Gábor Szederkényi, Dorottya Kocsis, Mihály A. Vághy, Domonkos Czárán, Péter Sasvári, Miléna Lengyel, Márton Bese Naszlady, Fabiola Kreis, István Antal, Roland Csépányi-Kömi, Franciska Erdő

published 11 Apr 2024

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Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models

Xiaojun Wang, Xiaohong Yu, Kostas Gavardinas, Asim Dey, Hong Y. Zhang, Gina Porter, Leah Porras, Lan Yu, Haihong Guo, Charles A. Reidy, Joseph V. Haas, Yanping Xu, Mark C. Kowala, Prabhakar K. Jadhav, John R. Wetterau

published 26 Jan 2024

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Secondary metabolites of Trichoderma spp. as EGFR tyrosine kinase inhibitors: Evaluation of anticancer efficacy through computational approach

H.G. Gowtham, Prasanna D. Revanasiddappa, Mahadevamurthy Murali, Sudarshana Brijesh Singh, M.R. Abhilash, Sushma Pradeep, Chandan Shivamallu, Raghu Ram Achar, Ekaterina Silina, Victor Stupin, Natalia Manturova, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Shiva Prasad Kollur

published 24 Jan 2024

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SuperNatural inhibitors to reverse multidrug resistance emerged by ABCB1 transporter: Database mining, lipid-mediated molecular dynamics, and pharmacokinetics study

Mahmoud A. A. Ibrahim, Khlood A. A. Abdeljawaad, Alaa H. M. Abdelrahman, Mahmoud M. H. Abdelhamid, Mohamed Ahmed Naeem, Gamal A. H. Mekhemer, Peter A. Sidhom, Shaban R. M. Sayed, Paul W. Paré, Mohamed-Elamir F. Hegazy

published 26 Jul 2023

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Repurposing the Medicines for Malaria Venture’s COVID Box to discover potent inhibitors of Toxoplasma gondii, and in vivo efficacy evaluation of almitrine bismesylate (MMV1804175) in chronically infected mice

Bruna Ramos dos Santos, Amanda Bruno da Silva Bellini Ramos, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Fábio Antônio Colombo, Marcos José Marques, Juliana Quero Reimão

published 07 Jul 2023

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Accelerated absorption of regular insulin administered via a vascularizing permeable microchamber implanted subcutaneously in diabetic Rattus norvegicus

Leah V. Steyn, Delaney Drew, Demetri Vlachos, Barry Huey, Katie Cocchi, Nicholas D. Price, Robert Johnson, Charles W. Putnam, Klearchos K. Papas

published 29 Jun 2023

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Validation of an omega-3 substrate challenge absorption test as an indicator of global fat lipolysis

Steven D. Freedman, Kamil Zaworski, Kateryna Pierzynowska, Stefan Pierzynowski, Robert Gallotto, Meghana Sathe, Drucy S. Borowitz

published 08 May 2023

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Determining reference ranges and sample sizes in parallel-group studies

Gwowen Shieh

published 30 Nov 2022

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A dose-finding safety and feasibility study of oral activated charcoal and its effects on the gut microbiota in healthy volunteers not receiving antibiotics

Armin Rashidi, Sathappan Karuppiah, Maryam Ebadi, Ryan Shanley, Alexander Khoruts, Daniel J. Weisdorf, Christopher Staley

published 14 Jun 2022

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Construction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization and In vivo clinical comparative pharmacokinetic study in healthy human subjects

Mahmoud Teaima, Mohamed Yasser, Nehal Elfar, Kamel Shoueir, Mohamed El-Nabarawi, Doaa Helal

published 09 Jun 2022

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