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Dose prediction methods

Pharmacokinetics, pharmacodynamics, safety, and tolerability of single-dose denosumab in healthy Chinese volunteers: A randomized, single-blind, placebo-controlled study

Qian Chen, Chaoying Hu, Yanmei Liu, Rong Song, Wenjing Zhu, Hongxin Zhao, Antonio Nino, Fan Zhang, Yun Liu

published 22 Jun 2018

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Effects of early diuretic response to carperitide in acute decompensated heart failure treatment: A single-center retrospective study

Yoshitaka Okuhara, Masanori Asakura, Kohei Azuma, Yoshiyuki Orihara, Koichi Nishimura, Tomotaka Ando, Hideyuki Kondo, Yoshiro Naito, Kazunori Kashiwase, Shinichi Hirotani, Masaharu Ishihara, Tohru Masuyama

published 18 Jun 2018

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Treatment patterns and steroid dose for adult minimal change disease relapses: A retrospective cohort study

Takaya Ozeki, Masahiko Ando, Makoto Yamaguchi, Takayuki Katsuno, Sawako Kato, Yoshinari Yasuda, Naotake Tsuboi, Shoichi Maruyama

published 18 Jun 2018

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Renal resistive index as an early predictor and discriminator of acute kidney injury in critically ill patients; A prospective observational cohort study

Jelle L. G. Haitsma Mulier, Sander Rozemeijer, Jantine G. Röttgering, Angelique M. E. Spoelstra-de Man, Paul W. G. Elbers, Pieter Roel Tuinman, Monique C. de Waard, Heleen M. Oudemans-van Straaten

published 11 Jun 2018

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An open-label, multiple ascending dose study of the anti-CTLA-4 antibody ipilimumab in viremic HIV patients

Elizabeth Colston, Dennis Grasela, David Gardiner, R. Pat Bucy, Blisse Vakkalagadda, Alan J. Korman, Israel Lowy

published 07 Jun 2018

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A novel statistical method for assessing effective adherence to medication and calculating optimal drug dosages

Garrett Greene, Richard W. Costello, Breda Cushen, Imran Sulaiman, Elaine Mac Hale, Ronan M. Conroy, Frank Doyle

published 20 Apr 2018

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Prediction of hemoglobin levels in individual hemodialysis patients by means of a mathematical model of erythropoiesis

Doris H. Fuertinger, Franz Kappel, Hanjie Zhang, Stephan Thijssen, Peter Kotanko

published 18 Apr 2018

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Pharmacokinetics and interspecies scaling of a novel, orally-bioavailable anti-cancer drug, SHetA2

Ankur Sharma, Doris Mangiaracina Benbrook, Sukyung Woo

published 10 Apr 2018

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Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody associated vasculitis: A retrospective cohort study

Arno C. Hessels, Abraham Rutgers, Jan Stephan F. Sanders, Coen A. Stegeman

published 09 Apr 2018

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Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation

Kalluri Thishya, Kiran Kumar Vattam, Shaik Mohammad Naushad, Shree Bhushan Raju, Vijay Kumar Kutala

published 05 Apr 2018

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Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children

Joy Benadiba, Marc Ansari, Maja Krajinovic, Marie-France Vachon, Michel Duval, Pierre Teira, Sonia Cellot, Henrique Bittencourt

published 02 Apr 2018

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Predicting short-term interruptions of antiretroviral therapy from summary adherence data: Development and test of a probability model

Rebecca Arden Harris, Jessica E. Haberer, Nicholas Musinguzi, Kyong-Mi Chang, Clyde B. Schechter, Chyke A. Doubeni, Robert Gross

published 22 Mar 2018

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Can transplant renal scintigraphy predict the duration of delayed graft function? A dual center retrospective study

Stan Benjamens, Robert A. Pol, Lioe-Fee de Geus-Oei, Aiko P. J. de Vries, Andor W. J. M. Glaudemans, Stefan P. Berger, Riemer H. J. A. Slart

published 21 Mar 2018

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