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Dose prediction methods

Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions

Gregory S. Honda, Robert G. Pearce, Ly L. Pham, R. W. Setzer, Barbara A. Wetmore, Nisha S. Sipes, Jon Gilbert, Briana Franz, Russell S. Thomas, John F. Wambaugh

published 28 May 2019

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Evaluating dose of cisplatin responsible for causing nephrotoxicity

Kyouko Higuchi, Takashi Yanagawa

published 25 Apr 2019

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Modelling the effective dose to a population from fallout after a nuclear power plant accident—A scenario-based study with mitigating actions

Mats Isaksson, Martin Tondel, Robert Wålinder, Christopher Rääf

published 09 Apr 2019

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First-in-human Phase I studies of PRS-080#22, a hepcidin antagonist, in healthy volunteers and patients with chronic kidney disease undergoing hemodialysis

Lutz Renders, Klemens Budde, Christian Rosenberger, Rachel van Swelm, Dorine Swinkels, Frank Dellanna, Werner Feuerer, Ming Wen, Christiane Erley, Birgit Bader, Claudia Sommerer, Matthias Schaier, Karoline Meurer, Louis Matis

published 27 Mar 2019

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Prognostic value of NT-proBNP added to clinical parameters to predict two-year prognosis of chronic heart failure patients with mid-range and reduced ejection fraction – A report from FAR NHL prospective registry

Jindrich Spinar, Lenka Spinarova, Filip Malek, Ondrej Ludka, Jan Krejci, Petr Ostadal, Dagmar Vondrakova, Karel Labr, Monika Spinarova, Monika Pavkova Goldbergova, Klara Benesova, Jiri Jarkovsky, Jiri Parenica

published 26 Mar 2019

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A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia

Antonio C. Arrieta, Lillian Sung, John S. Bradley, C. Michel Zwaan, Davis Gates, Hetty Waskin, Patricia Carmelitano, Andreas H. Groll, Thomas Lehrnbecher, Eric Mangin, Amita Joshi, Nicholas A. Kartsonis, Thomas J. Walsh, Amanda Paschke

published 26 Mar 2019

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Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis

Joaquim Calvo-Lerma, Jessie Hulst, Mieke Boon, Carla Colombo, Etna Masip, Mar Ruperto, Victoria Fornés-Ferrer, Els van der Wiel, Ine Claes, Maria Garriga, Maria Roca, Paula Crespo-Escobar, Anna Bulfamante, Sandra Woodcock, Sandra Martínez-Barona, Ana Andrés, Kris de Boeck, Carmen Ribes-Koninckx, on behalf of MyCyFAPP project

published 12 Mar 2019

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Impact of nominal photon energies on normal tissue sparing in knowledge-based radiotherapy treatment planning for rectal cancer patients

Yuliang Huang, Sha Li, Haizhen Yue, Meijiao Wang, Qiaoqiao Hu, Haiyang Wang, Tian Li, Chenguang Li, Hao Wu, Yibao Zhang

published 07 Mar 2019

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A first approach for an evidence-based in vitro digestion method to adjust pancreatic enzyme replacement therapy in cystic fibrosis

Joaquim Calvo-Lerma, Victoria Fornés-Ferrer, Irene Peinado, Ana Heredia, Carmen Ribes-Koninckx, Ana Andrés

published 22 Feb 2019

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Vaccination timeliness among newborns and infants in Ethiopia

Matthew L. Boulton, Bradley F. Carlson, Abram L. Wagner, Julia M. Porth, Berhanu Gebremeskel, Yemesrach Abeje

published 19 Feb 2019

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Highly efficient and sensitive patient-specific quality assurance for spot-scanned proton therapy

J. E. Johnson, C. Beltran, H. Wan Chan Tseung, D. W. Mundy, J. J. Kruse, T. J. Whitaker, M. G. Herman, K. M. Furutani

published 14 Feb 2019

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Adherence to intermittent preventive treatment for malaria in Papua New Guinean infants: A pharmacological study alongside the randomized controlled trial

Oriane Sottas, Monia Guidi, Benjamin Thieffry, Marie Schneider, Laurent Décosterd, Ivo Mueller, Blaise Genton, Chantal Csajka, Nicolas Senn

published 06 Feb 2019

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Predictive genomic markers of response to VEGF targeted therapy in metastatic renal cell carcinoma

David D. Stenehjem, Andrew W. Hahn, David M. Gill, Daniel Albertson, Banumathy Gowrishankar, Joseph Merriman, Archana M. Agarwal, Venkata Thodima, Erik B. Harrington, Trang H. Au, Benjamin L. Maughan, Jane Houldsworth, Sumanta K. Pal, Neeraj Agarwal

published 25 Jan 2019

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