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Dose prediction methods

Pharmacokinetic model selection for infliximab based on inflammatory bowel disease phenotype and severity: Toward model-informed precision dosing

Ana Homšek Ilić, Marija Jovanović, Srđan Marković, Sandra Vezmar Kovačević, Tamara Knežević Ivanovski, Đorđe Kralj, Petar Svorcan, Katarina Vučićević

published 24 Jul 2026

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Optimal exercise modalities and dosages for improving depression in middle-aged and older adults with Parkinson's disease: A Bayesian Dose–response network meta-analysis

Yiang Lyu, Jiawei Chen, Siqin Zeng

published 23 Jul 2026

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Thyroid V40 as a potential early predictor of hypothyroidism following hypofractionated locoregional breast radiotherapy

Moemen Khalifa, Maher Soliman, Abbas Omar, Mohamed Abouegylah, Amr Munir Ameen, Yomna Mahmoud Mohamad, Waleed Arafat

published 18 Jun 2026

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CACE closed: A multiverse examination of the influence of implementation variability on student outcomes in a randomised controlled trial of a universal, school-based social-emotional learning intervention

Annie O’Brien, Joao Santos, Neil Humphrey, Margarita Panayiotou

published 02 Jun 2026

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Risk factors for post-induction hypotension in patients with end-stage renal disease undergoing general anesthesia

Supachai Trikisayaveach, Laortip Rattanapittayaporn, Jatuporn Pakpirom, Chutida Sungworawongpana, Suttasinee Petsakul

published 29 May 2026

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DeepDRP: Dose-response predictions of drug pairs using deep learning based on data-driven feature representation and dose-response curve characteristics

Mohammadamin Moragheb, Alireza Dehghan, Parvin Razzaghi, Sajjad Gharaghani

published 08 May 2026

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Machine learning-based unified models for predicting drug clearance from pharmacokinetic animal and study design variables

Remya Ampadi Ramachandran, Lisa A. Tell, Melissa A. Mercer, Xuan Xu, Nuwan Indika Millagaha Gedara, Maaike Ottoline Clapham, Zhoumeng Lin, Jim E. Riviere, Majid Jaberi-Douraki

published 06 May 2026

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Development and evaluation of a multimodal feature-based predictive model for radiotherapy-induced oral mucositis in nasopharyngeal carcinoma

Ling Li, Linke Li, Ruifeng Guo, Shiting Fang, Ke Wang, Ge Yuan, Danxian Jiang, Jing Huang

published 09 Apr 2026

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Factors Predicting successful treatment outcome with novel BPaLM/BPaL regimen in individuals with drug-resistant tuberculosis: Experience From Indonesia

Arto Yuwono Soeroto, Aga Purwiga, Hendarsyah Suryadinata, Bachti Alisjahbana, Afiatin Makmun, Yana Akhmad Supriatna, Emmy Hermiyanti Pranggono, Bony Wiem Lestari

published 01 Apr 2026

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Hepatic transcriptomic responses in gravid and non-gravid rats exposed to HFPO-DA: Analyses to inform the role of maternal effects in neonatal toxicity

Melissa M. Heintz, Chad M. Thompson, Jeffrey C. Wolf, John M. Rogers, Laurie C. Haws

published 01 Apr 2026

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Prediction of adherence to treatment with statins and anti-platelet drugs in first-year post-stroke patients: Validation of beta-regression models

Elias Edward Tannous, Shlomo Vinker, David Stepensky, Eyal Schwarzberg

published 26 Mar 2026

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A computational method to estimate the relative biological effectiveness and tumor control probability for low-LET proton irradiations

Chun-Chieh Chan, Kuang-Lung Hsueh, Chung-Yu Lai, Ya-Yun Hsiao

published 20 Mar 2026

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Innate defense mechanisms against Nosema ceranae in hygienic honey bee (Apis mellifera) colonies

M. Sydney Miller, Dawn Boncristiani, Jay Evans, P. Alexander Burnham, Cailin Barrett, Kaira Wagoner, Samantha A. Alger

published 04 Mar 2026

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