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Dimerization

The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles

Y. Rose Citron, Carey J. Fagerstrom, Bettina Keszthelyi, Bo Huang, Nasser M. Rusan, Mark J. S. Kelly, David A. Agard

published 09 Jan 2018

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Molecular dynamics simulations of the glucocorticoid receptor DNA-binding domain suggest a role of the lever-arm mobility in transcriptional output

Lautaro Damián Álvarez, Diego Martín Presman, Adalí Pecci

published 15 Dec 2017

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A general model for predicting the binding affinity of reversibly and irreversibly dimerized ligands

Kenneth W. Foreman

published 22 Nov 2017

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Excessive aggregation of membrane proteins in the Martini model

Matti Javanainen, Hector Martinez-Seara, Ilpo Vattulainen

published 13 Nov 2017

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Biological activity and dimerization state of modified phytochrome A proteins

Peng Liu, Robert A. Sharrock

published 19 Oct 2017

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Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking

Alice A. Royal, Andrew Tinker, Stephen C. Harmer

published 11 Oct 2017

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The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3’-end processing

Wei Shen Aik, Min-Han Lin, Dazhi Tan, Ashutosh Tripathy, William F. Marzluff, Zbigniew Dominski, Chi-Yuan Chou, Liang Tong

published 11 Oct 2017

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Heterodimerization of two pore domain K⁺ channel TASK1 and TALK2 in living heterologous expression systems

Yoshiaki Suzuki, Kanako Tsutsumi, Tatsuya Miyamoto, Hisao Yamamura, Yuji Imaizumi

published 10 Oct 2017

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Species A rotavirus NSP3 acquires its translation inhibitory function prior to stable dimer formation

Hugo I. Contreras-Treviño, Edgar Reyna-Rosas, Renato León-Rodríguez, Blanca H. Ruiz-Ordaz, Tzvetanka D. Dinkova, Ana M. Cevallos, Luis Padilla-Noriega

published 24 Jul 2017

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Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis

Wanting Jiao, Nicola J. Blackmore, Ali Reza Nazmi, Emily J. Parker

published 30 Jun 2017

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Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain

Chia-Lun Wu, Serge Hardy, Isabelle Aubry, Melissa Landry, Allison Haggarty, Horacio Uri Saragovi, Michel L. Tremblay

published 30 May 2017

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D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain

Ahmet S. Vakkasoglu, Sriram Srikant, Rachelle Gaudet

published 23 May 2017

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Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation

Erika Pellegrini, Luca Signor, Saurabh Singh, Elisabetta Boeri Erba, Stephen Cusack

published 18 May 2017

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