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Deletion mutation

Deletion of MHY1 abolishes hyphae formation in Yarrowia lipolytica without negative effects on stress tolerance

Oliver Konzock, Joakim Norbeck

published 03 Apr 2020

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Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer

Sindhu Nair, Hoa Q. Trummell, Rajani Rajbhandari, Nanda K. Thudi, Susan E. Nozell, Jason M. Warram, Christopher D. Willey, Eddy S. Yang, William J. Placzek, James A. Bonner, Markus Bredel

published 18 Feb 2020

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Clinical significance of EGFR mutation types in lung adenocarcinoma: A multi-centre Korean study

Hee-Young Yoon, Jeong-Seon Ryu, Yun Su Sim, Dojin Kim, Sung Yong Lee, Juwhan Choi, Sojung Park, Yon Ju Ryu, Jin Hwa Lee, Jung Hyun Chang

published 13 Feb 2020

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Molecular characterization of lung adenocarcinoma from Korean patients using next generation sequencing

You Jin Chun, Jae Woo Choi, Min Hee Hong, Dongmin Jung, Hyeonju Son, Eun Kyung Cho, Young Joo Min, Sang-We Kim, Keunchil Park, Sung Sook Lee, Sangwoo Kim, Hye Ryun Kim, Byoung Chul Cho, Korean Lung Cancer Consortium (KLCC)

published 25 Nov 2019

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Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase

Hoshie Iriki, Takefumi Kawata, Tetsuya Muramoto

published 17 Oct 2019

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Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy

Olivier Ballo, Jan Stratmann, Hubert Serve, Björn Steffen, Fabian Finkelmeier, Christian Brandts

published 30 Sep 2019

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Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation

Mahlet Z. Tamirat, Marika Koivu, Klaus Elenius, Mark S. Johnson

published 19 Sep 2019

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MET exon 14 skipping mutations and gene amplification in a Taiwanese lung cancer population

Jrhau Lung, Ming-Szu Hung, Yu-Ching Lin, Kam-Fai Lee, Yuan Yuan Jiang, Shao-Lan Huang, Yu-Hung Fang, Ming-Shian Lu, Chin-Kuo Lin, Tsung-Ming Yang, Paul Yann Lin, Meng-Jer Hsieh, Ying Huang Tsai

published 01 Aug 2019

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Constitutive STAT5 phosphorylation in CD34⁺ cells of patients with primary myelofibrosis: Correlation with driver mutation status and disease severity

Carlotta Abbà, Rita Campanelli, Paolo Catarsi, Laura Villani, Vittorio Abbonante, Melania Antonietta Sesta, Giovanni Barosi, Vittorio Rosti, Margherita Massa

published 01 Aug 2019

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Functional association of Loc1 and Puf6 with RNA helicase Dhh1 in translational regulation of Saccharomyces cerevisiae Ste12

Daehee Jung, Jong Seok Seo, Jayoung Nam, Jinmi Kim

published 19 Jul 2019

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Deletion of the major Escherichia coli multidrug transporter AcrB reveals transporter plasticity and redundancy in bacterial cells

Noémie Alon Cudkowicz, Shimon Schuldiner

published 28 Jun 2019

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Development of a markerless gene deletion strategy using rpsL as a counterselectable marker and characterization of the function of RA0C_1534 in Riemerella anatipestifer ATCC11845 using this strategy

MaFeng Liu, Xiu Tian, MengYi Wang, DeKang Zhu, MingShu Wang, RenYong Jia, Shun Chen, XinXin Zhao, Qiao Yang, Ying Wu, ShaQiu Zhang, Juan Huang, Bin Tian, XiaoYue Chen, YunYa Liu, Ling Zhang, YanLing Yu, Francis Biville, LeiChang Pan, Mujeeb Ur Rehman, AnChun Cheng

published 10 Jun 2019

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Lessening of porcine epidemic diarrhoea virus susceptibility in piglets after editing of the CMP-N-glycolylneuraminic acid hydroxylase gene with CRISPR/Cas9 to nullify N-glycolylneuraminic acid expression

Ching-Fu Tu, Chin-kai Chuang, Kai-Hsuan Hsiao, Chien-Hong Chen, Chi-Min Chen, Su-Hei Peng, Yu-Hsiu Su, Ming-Tang Chiou, Chon-Ho Yen, Shao-Wen Hung, Tien-Shuh Yang, Chuan-Mu Chen

published 29 May 2019

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