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Rigorous nested cross-validation and external generalization-gap analysis of a machine-learning classifier for U-251 glioblastoma cytotoxicity

Yuki Uemichi, Shuhei Nakao, Shuji Nagano, Miyuki Mabuchi, Yuya Kawabata, Yoshihiro Uesawa, Tadashi Shimizu

published 03 Nov 2026

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Strengthening continuity of care for multiple long-term conditions in India through integrated referral and follow-up systems (SYNC-RF): A mixed-methods study protocol

Girish Chandra Dash, Samuel Seidu, Anneka Welford, Riya Patel, Patrick Highton, Kamlesh Khunti, Dorairaj Prabhakaran, Sailesh Mohan

published 03 Nov 2026

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Spreading the Joy of Literacy: A community-based survey of parents by parents

Sarah Collins-McGowan, Claude Andrew Aligne, Kelly McDermott, Candace Cabral, Ana Pilar Ramos Benitez, Melissa Lomack, Nicole Mayo

published 03 Nov 2026

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Light meal consumption among university students in China: A multi-regional cross-sectional study of behavioral patterns, influencing factors, and service optimization strategies under supply-side heterogeneity

Hairu Zhang, Baoqi Zhou, Jiaxin Wang, Yue Li

published 03 Nov 2026

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Aromatic profiles and 15-LOX inhibitory effects of Australian and New Zealand Manuka honeys

Georgia Moore, Asmaa Boufridi, Fraser Russell, Peter Brooks

published 03 Nov 2026

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Equivalent linearization modeling and experimental validation of natural frequency and vibration isolation performance in metal braided hoses

Dacheng Huang, Yue Liu, Dongqin Li, Jianrun Zhang

published 03 Nov 2026

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Clinical and ocular factors associated with visual field progression following optic disc haemorrhage in glaucoma

Haewon Lee, Ji Eun Song, Seong Ho Kim, Byeong Seok Kim, Yongwoo Lee

published 03 Nov 2026

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Endoscopic necrosectomy of infected pancreatic Walled-Off Necrosis using two types of Lumen-Apposing Metal Stents

Cong Ding, Hui Wang, Yifeng Zhou, Jing Yang, Xia Wang, Goufan Shen, Xiaofeng Zhang, Richard Hu, Jianfeng Yang

published 03 Nov 2026

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Expression of Concern: Modeling the impacts of natural and human factors on the hatching success of the loggerhead sea turtle Caretta caretta along the coasts of Italy

The PLOS One Editors

published 03 Nov 2026

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Sex and educational inequalities across functional ability trajectories in Chile: A sequence analysis of a 17-year national panel

Ignacio Cabib, Pablo Villalobos Dintrans, Jorge Browne Salas

published 03 Nov 2026

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PIVKA-II and hematological parameters in hepatocellular carcinoma and non-malignant chronic liver disease: A case-control biomarker comparison in a hepatitis-endemic population

Muhammad Sameer Hashmi, Muhammad Aqif Ilyas

published 03 Nov 2026

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Relational learning cues, music receptivity, and performance self-efficacy among piano masterclass participants: A PLS-SEM and fsQCA study

Yixuan Zhao, Xiaohui Zhu, Yan Su

published 03 Nov 2026

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Unveiling the neuroinflammatory potential of aspartame in Alzheimer’s disease: A comprehensive network toxicology and experimental validation approach

Dongyang Li, Xuejun Weng, Yijuan Huang, Dongni Yang, Shunhan Yao, Weihao Zheng, Xiaohong Jiang, Yilin Wei, Sheng Xu, Chunwei Wei

published 03 Nov 2026

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