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Cytotoxicity

Identification of New Molecular Entities (NMEs) as Potential Leads against Tuberculosis from Open Source Compound Repository

Sudha Sravanti Kotapalli, Sri Satya Anila Nallam, [ ... ], Ramesh Ummanni

Fentanyl Enhances Hepatotoxicity of Paclitaxel via Inhibition of CYP3A4 and ABCB1 Transport Activity in Mice

Jing-Dun Xie, Yang Huang, [ ... ], Wei-An Zeng

Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells

Rikio Suzuki, Shohei Kikuchi, [ ... ], Kenneth C. Anderson

Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins

Shandee D. Dixon, Melanie M. Huynh, [ ... ], Kenneth A. Bradley

Organometallic Half-Sandwich Dichloridoruthenium(II) Complexes with 7-Azaindoles: Synthesis, Characterization and Elucidation of Their Anticancer Inactivity against A2780 Cell Line

Pavel Štarha, Lucie Hanousková, Zdeněk Trávníček

Toxicity Minimized Cryoprotectant Addition and Removal Procedures for Adherent Endothelial Cells

Allyson Fry Davidson, Cameron Glasscock, [ ... ], Adam Z. Higgins

Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification

Srijata Sarkar, Bey Fen Leo, [ ... ], Stephan Schwander

Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta_25–35 via the Autophagy Pathway

Pengjuan Xu, Zhigui Li, [ ... ], Zhuo Yang

Genotoxicity and Cytotoxicity Evaluation of the Neolignan Analogue 2-(4-Nitrophenoxy)-1Phenylethanone and its Protective Effect Against DNA Damage

Alex Lucas Hanusch, Guilherme Roberto de Oliveira, [ ... ], Lee Chen Chen

Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells

Nilesh K. Sharma, Ashutosh Kumar, [ ... ], Birandra K. Sinha

A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy

Thu Le Trinh, Guizhi Zhu, [ ... ], Chen Liu

Dispersion Behaviour of Silica Nanoparticles in Biological Media and Its Influence on Cellular Uptake

Blanka Halamoda-Kenzaoui, Mara Ceridono, [ ... ], Agnieszka Kinsner-Ovaskainen

Combining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug Discovery

Sean Ekins, Peter B. Madrid, [ ... ], Joel S. Freundlich

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