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Crystal structure

Binding of an Indenoisoquinoline to the Topoisomerase-DNA Complex Induces Reduction of Linker Mobility and Strengthening of Protein-DNA Interaction

Giordano Mancini, Ilda D’Annessa, [ ... ], Alessandro Desideri

Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6

Christopher E. Heise, Jeremy Murray, [ ... ], Michelle R. Arkin

Structural Dynamics of Troponin I during Ca2+-Activation of Cardiac Thin Filaments: A Multi-Site Förster Resonance Energy Transfer Study

Hui Wang, Joseph M. Chalovich, Gerard Marriott

Identification of Elements That Dictate the Specificity of Mitochondrial Hsp60 for Its Co-Chaperonin

Avital Parnas, Shahar Nisemblat, [ ... ], Abdussalam Azem

Structural and Biochemical Studies on ATP Binding and Hydrolysis by the Escherichia coli RNA Chaperone Hfq

Hermann Hämmerle, Mads Beich-Frandsen, [ ... ], Udo Bläsi

Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation

Laura Guasch, Esther Sala, [ ... ], Santiago Garcia-Vallvé

Crystal Structure of Circular Permuted RoCBM21 (CP90): Dimerisation and Proximity of Binding Sites

Preyesh Stephen, Kuo-Chang Cheng, Ping-Chiang Lyu

Molecular Modeling Study on Tunnel Behavior in Different Histone Deacetylase Isoforms

Sundarapandian Thangapandian, Shalini John, [ ... ], Keun Woo Lee

Exploring ORFan Domains in Giant Viruses: Structure of Mimivirus Sulfhydryl Oxidase R596

Motti Hakim, Daria Ezerina, [ ... ], Deborah Fass

Ebola Virus Genome Plasticity as a Marker of Its Passaging History: A Comparison of In Vitro Passaging to Non-Human Primate Infection

Jeffrey R. Kugelman, Michael S. Lee, [ ... ], Gustavo Palacios

Solution Structures, Dynamics, and Ice Growth Inhibitory Activity of Peptide Fragments Derived from an Antarctic Yeast Protein

Syed Hussinien H. Shah, Rajiv K. Kar, [ ... ], Anirban Bhunia

Crystal Structure of the Hexachlorocyclohexane Dehydrochlorinase (LinA-Type2): Mutational Analysis, Thermostability and Enantioselectivity

Ankit S. Macwan, Vandna Kukshal, [ ... ], Ravishankar Ramachandran

NADP⁺ Binding to the Regulatory Subunit of Methionine Adenosyltransferase II Increases Intersubunit Binding Affinity in the Hetero-Trimer

Beatriz González, Francisco Garrido, [ ... ], María A. Pajares

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