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CRISPR

Off-target effects of CRISPRa on interleukin-6 expression

Sébastien Soubeyrand, Paulina Lau, Victoria Peters, Ruth McPherson

published 28 Oct 2019

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Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development

Anirban Roy, Ying Zhai, Jessica Ortiz, Michael Neff, Bikash Mandal, Sunil Kumar Mukherjee, Hanu R. Pappu

published 23 Oct 2019

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Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase

Hoshie Iriki, Takefumi Kawata, Tetsuya Muramoto

published 17 Oct 2019

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Integration of a FT expression cassette into CRISPR/Cas9 construct enables fast generation and easy identification of transgene-free mutants in Arabidopsis

Yuxin Cheng, Na Zhang, Saddam Hussain, Sajjad Ahmed, Wenting Yang, Shucai Wang

published 23 Sep 2019

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Analysis of Zobellella denitrificans ZD1 draft genome: Genes and gene clusters responsible for high polyhydroxybutyrate (PHB) production from glycerol under saline conditions and its CRISPR-Cas system

Yu-Wei Wu, Shih-Hung Yang, Myung Hwangbo, Kung-Hui Chu

published 12 Sep 2019

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CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition

Wanlu Li, Mee-Yon Cho, Suji Lee, Mirae Jang, Junsoo Park, Rackhyun Park

published 08 Aug 2019

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TET1 is an important transcriptional activator of TNFα expression in macrophages

Fangfang Sun, Irene Abreu-Rodriguez, Shuang Ye, Steffen Gay, Oliver Distler, Michel Neidhart, Emmanuel Karouzakis

published 19 Jun 2019

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Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency

Ignacio García-Tuñón, Verónica Alonso-Pérez, Elena Vuelta, Sandra Pérez- Ramos, María Herrero, Lucía Méndez, Jesús María Hernández-Sánchez, Marta Martín-Izquierdo, Raquel Saldaña, Julián Sevilla, Fermín Sánchez- Guijo, Jesús María Hernández-Rivas, Manuel Sánchez-Martín

published 09 May 2019

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Genetic characterisation of variants of the virulence plasmid, pSLT, in Salmonella enterica serovar Typhimurium provides evidence of a variety of evolutionary directions consistent with vertical rather than horizontal transmission

Lester Hiley, Rikki M. A. Graham, Amy V. Jennison

published 11 Apr 2019

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Comparison of efficiency and specificity of CRISPR-associated (Cas) nucleases in plants: An expanded toolkit for precision genome engineering

Oleg Raitskin, Christian Schudoma, Anthony West, Nicola J. Patron

published 27 Feb 2019

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CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review

Haris Babačić, Aditi Mehta, Olivia Merkel, Benedikt Schoser

published 22 Feb 2019

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Generation of TGFBI knockout ABCG2+/ABCB5+ double-positive limbal epithelial stem cells by CRISPR/Cas9-mediated genome editing

Eung Kweon Kim, Seunghyuk Kim, Yong-Sun Maeng

published 12 Feb 2019

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Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts

Stijn Mertens, Brigida Gallone, Jan Steensels, Beatriz Herrera-Malaver, Jeroen Cortebeek, Robbe Nolmans, Veerle Saels, Valmik K. Vyas, Kevin J. Verstrepen

published 09 Jan 2019

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