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Connective tissue

Pharmacokinetics (PK), Pharmacodynamics (PD) and Integrated PK/PD Modeling of a Novel Long Acting FGF21 Clinical Candidate PF-05231023 in Diet-Induced Obese and Leptin-Deficient Obese Mice

Yan Weng, Jeffrey R. Chabot, Barbara Bernardo, Qingyun Yan, Yimin Zhu, Martin B. Brenner, Chandra Vage, Alison Logan, Roberto Calle, Saswata Talukdar

published 19 Mar 2015

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In Vitro Culture of Functionally Active Buffalo Hepatocytes Isolated by Using a Simplified Manual Perfusion Method

Santanu Panda, Sonu Bisht, Dhruba Malakar, Ashok K. Mohanty, Jai K. Kaushik

published 19 Mar 2015

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Development of a Prototype Over-Actuated Biomimetic Prosthetic Hand

Matthew R. Williams, Wayne Walter

published 19 Mar 2015

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A Pilot Study of Omalizumab in Eosinophilic Esophagitis

Denise Loizou, Benjamin Enav, Edina Komlodi-Pasztor, Pamela Hider, Julie Kim-Chang, Laura Noonan, Tabitha Taber, Suhasini Kaushal, Renuka Limgala, Margaret Brown, Raavi Gupta, Nader Balba, Ozlem Goker-Alpan, Amer Khojah, Oral Alpan

published 19 Mar 2015

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Aging-Related Systemic Manifestations in COPD Patients and Cigarette Smokers

Laurent Boyer, Christos Chouaïd, Sylvie Bastuji-Garin, Elisabeth Marcos, Laurent Margarit, Philippe Le Corvoisier, Laetitia Vervoitte, Leila Hamidou, Lamia Frih, Etienne Audureau, Ala Covali-Noroc, Pascal Andujar, Zakaria Saakashvili, Anne Lino, Bijan Ghaleh, Sophie Hue, Geneviève Derumeaux, Bruno Housset, Jean-Luc Dubois-Randé, Jorge Boczkowski, Bernard Maitre, Serge Adnot

published 18 Mar 2015

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Knockdown of CDK2AP1 in Primary Human Fibroblasts Induces p53 Dependent Senescence

Khaled N. Alsayegh, Venkat S. Gadepalli, Shilpa Iyer, Raj R. Rao

published 18 Mar 2015

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Mechanical Properties of the Compass Depressors of the Sea-Urchin Paracentrotus lividus (Echinodermata, Echinoidea) and the Effects of Enzymes, Neurotransmitters and Synthetic Tensilin-Like Protein

Iain C. Wilkie, Dario Fassini, Emanuele Cullorà, Alice Barbaglio, Serena Tricarico, Michela Sugni, Luca Del Giacco, M. Daniela Candia Carnevali

published 18 Mar 2015

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Body Fat Accumulation in Zebrafish Is Induced by a Diet Rich in Fat and Reduced by Supplementation with Green Tea Extract

Shinichi Meguro, Takahiro Hasumura, Tadashi Hase

published 18 Mar 2015

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Direct Determination of Phosphatase Activity from Physiological Substrates in Cells

Zhongyuan Ren, Le Duy Do, Géraldine Bechkoff, Saida Mebarek, Nermin Keloglu, Saandia Ahamada, Saurabh Meena, David Magne, Slawomir Pikula, Yuqing Wu, René Buchet

published 18 Mar 2015

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Thermally Induced Osteocyte Damage Initiates a Remodelling Signaling Cascade

Eimear B. Dolan, Matthew G. Haugh, Muriel C. Voisin, David Tallon, Laoise M. McNamara

published 18 Mar 2015

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Stromal Cells Positively and Negatively Modulate the Growth of Cancer Cells: Stimulation via the PGE2-TNFα-IL-6 Pathway and Inhibition via Secreted GAPDH-E-Cadherin Interaction

Manabu Kawada, Hiroyuki Inoue, Shun-ichi Ohba, Junjiro Yoshida, Tohru Masuda, Manabu Yamasaki, Ihomi Usami, Shuichi Sakamoto, Hikaru Abe, Takumi Watanabe, Takao Yamori, Masakatsu Shibasaki, Akio Nomoto

published 18 Mar 2015

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Comparative Genomic Analysis of Buffalo (Bubalus bubalis) NOD1 and NOD2 Receptors and Their Functional Role in In-Vitro Cellular Immune Response

Biswajit Brahma, Sushil Kumar, Bidhan Chandra De, Purusottam Mishra, Mahesh Chandra Patra, Deepak Gaur, Meenu Chopra, Devika Gautam, Sourav Mahanty, Hrudananda Malik, Dhruba Malakar, Tirtha Kumar Datta, Sachinandan De

published 18 Mar 2015

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Dystrophic Spinal Deformities in a Neurofibromatosis Type 1 Murine Model

Steven D. Rhodes, Wei Zhang, Dalong Yang, Hao Yang, Shi Chen, Xiaohua Wu, Xiaohong Li, Xianlin Yang, Khalid S. Mohammad, Theresa A. Guise, Amanda L. Bergner, David A. Stevenson, Feng-Chun Yang

published 18 Mar 2015

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