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Complement system

C1-inactivator is upregulated in glioblastoma

Karolina Förnvik, Aida Maddahi, Oscar Persson, Kurt Osther, Leif G. Salford, Henrietta Nittby Redebrandt

published 07 Sep 2017

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Complement inhibition attenuates acute kidney injury after ischemia-reperfusion and limits progression to renal fibrosis in mice

Juan S. Danobeitia, Martynas Ziemelis, Xiaobo Ma, Laura J. Zitur, Tiffany Zens, Peter J. Chlebeck, Edwin S. Van Amersfoort, Luis A. Fernandez

published 23 Aug 2017

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The species origin of the serum in the culture medium influences the in vitro toxicity of silica nanoparticles to HepG2 cells

Cédric Pisani, Estelle Rascol, Christophe Dorandeu, Jean-Charles Gaillard, Clarence Charnay, Yannick Guari, Joël Chopineau, Jean Armengaud, Jean-Marie Devoisselle, Odette Prat

published 10 Aug 2017

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Knockout of the gamma subunit of the AP-1 adaptor complex in the human parasite Trypanosoma cruzi impairs infectivity and differentiation and prevents the maturation and targeting of the major protease cruzipain

Claudia Maria do Nascimento Moreira, Cassiano Martin Batista, Jessica Chimenes Fernandes, Rafael Luis Kessler, Maurilio José Soares, Stenio Perdigão Fragoso

published 31 Jul 2017

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Human Tamm-Horsfall protein, a renal specific protein, serves as a cofactor in complement 3b degradation

Diana C. J. Rhodes

published 24 Jul 2017

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Tissue plasminogen activator mediates deleterious complement cascade activation in stroke

Xue-Jun Zhao, Timothy M. Larkin, Molly A. Lauver, Saif Ahmad, Andrew F. Ducruet

published 10 Jul 2017

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V1V2-specific complement activating serum IgG as a correlate of reduced HIV-1 infection risk in RV144

Lautaro G. Perez, David R. Martinez, Allan C. deCamp, Abraham Pinter, Phillip W. Berman, Donald Francis, Faruk Sinangil, Carter Lee, Kelli Greene, Hongmei Gao, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Jaranit Kaewkungwal, Punnee Pitisuttithum, James Tartaglia, Robert J. O’Connell, Merlin L. Robb, Nelson L. Michael, Jerome H. Kim, Peter Gilbert, David C. Montefiori

published 05 Jul 2017

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Systemic complement activation in central serous chorioretinopathy

Elon H. C. van Dijk, Roula Tsonaka, Ngaisah Klar-Mohamad, Diana Wouters, Aiko P. J. de Vries, Eiko K. de Jong, Cees van Kooten, Camiel J. F. Boon

published 03 Jul 2017

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Expression of Rickettsia Adr2 protein in E. coli is sufficient to promote resistance to complement-mediated killing, but not adherence to mammalian cells

Daniel A. Garza, Sean P. Riley, Juan J. Martinez

published 29 Jun 2017

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Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury

Nicholas Chun, Ala S. Haddadin, Junying Liu, Yunfang Hou, Karen A. Wong, Daniel Lee, Julie I. Rushbrook, Karan Gulaya, Roberta Hines, Tamika Hollis, Beatriz Nistal Nuno, Abeel A. Mangi, Sabet Hashim, Marcela Pekna, Amy Catalfamo, Hsiao-ying Chin, Foramben Patel, Sravani Rayala, Ketan Shevde, Peter S. Heeger, Ming Zhang

published 29 Jun 2017

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Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibody

Mark T. Winkler, Ryan T. Bushey, Elizabeth B. Gottlin, Michael J. Campa, Eross S. Guadalupe, Alicia D. Volkheimer, J. Brice Weinberg, Edward F. Patz Jr.

published 28 Jun 2017

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The role of insulin resistance in experimental diabetic retinopathy—Genetic and molecular aspects

Patrick Järgen, Axel Dietrich, Andreas W. Herling, Hans-Peter Hammes, Paulus Wohlfart

published 02 Jun 2017

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Increase in complement iC3b is associated with anti-inflammatory cytokine expression during late pregnancy in mice

Keigo Nakamura, Kazuya Kusama, Rulan Bai, Sadamasa Ishikawa, Sayuri Fukushima, Yoshihito Suda, Kazuhiko Imakawa

published 25 May 2017

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