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Complement system

Exploring proteomic signatures in sepsis and non-infectious systemic inflammatory response syndrome

Adolfo Ruiz-Sanmartín, Vicent Ribas, David Suñol, Luis Chiscano-Camón, Laura Martín, Iván Bajaña, Juliana Bastida, Nieves Larrosa, Juan José González, María Dolores Carrasco, Núria Canela, Ricard Ferrer, Juan Carlos Ruiz-Rodríguez

published 24 Apr 2026

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An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge

Daniel Palmer, Atieh Shemshadian, Katherine Berman, Ariana Nobles, Graham G. Willsey, Carol Lyn Piazza, Grace Freeman-Gallant, Michael J. Rudolph, Jeff Bourgeois, Linden Hu, David J. Vance, Nicholas J. Mantis

published 12 Mar 2026

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Salmonella enterica persister cells exhibit distinct susceptibility profiles following exposure to human serum and macrophages

Rodrigo Lira Rodrigues, Júlia Abreu da Rosa, Douglas Diefenbach da Cunha, Thaís Lima Nunes, Pedro Maria Abreu Ferreira, Bruno Kendi Makiyama, Florencia María Barbé-Tuana, Sílvia Dias de Oliveira, Carlos Alexandre Sanchez Ferreira

published 06 Mar 2026

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Mixed effects of complement in a chronic murine model of inflammatory erosive arthritis and pulmonary vascular disease

Kiana L. Chen, Stacey Duemmel, Michael Christof, Gaochan Wang, H. Mark Kenney, Marc Nuzzo, Qingfu Xu, Benjamin Korman, Homaira Rahimi

published 05 Feb 2026

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Real-world study: Assessing the impact of hemolysis on 48 biochemical and immunological analytes through big data analysis and its feasibility validation

Chaochao Ma, Xiaoqi Li, Wei Luo, Lian Hou, Dandan Sun, Li Liu, Xin Liu, Ying Zhang, Jingrong Xu, Ling Qiu, Liangyu Xia

published 23 Jan 2026

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Characterization of p53 p.T253I as a pathogenic mutation underlying Li-Fraumeni Syndrome

Nathaniel C. Holcomb, Amanda M. Harrington, Hong Pu, Berina Halilovic, Nathan R. Shelman, Shulin Zhang, Catherine Sears, Terra Armstrong, Brent Shelton, Lauren Corum, John A. D'Orazio

published 05 Dec 2025

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An electrophoretic mobility shift assay with chemiluminescent readout to evaluate DNA-targeting oligonucleotide-based probes

Michaela E. Everly, Peter J. Wieber, Ibrahim Al Janabi, Patrick J. Hrdlicka

published 30 Oct 2025

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Complement activation assessed by C3bc and C5b-9 terminal complex as diagnostic biomarkers for deep vein thrombosis

Vårin Eiriksdatter Wikan, Øyvind Øverli, Thor Ueland, Tom Eirik Mollnes, Sigrid Kufaas Brækkan, Annika Elisabet Michelsen, Gholamreza Jafari Yeganeh, John-Bjarne Hansen, Ellen Elisabeth Brodin

published 06 Oct 2025

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Eculizumab and ravulizumab clinical trial and real-world pharmacovigilance of meningococcal infections across indications

Cynthia Carrillo Infante, Arshad Mujeebuddin

published 12 Sep 2025

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Plasma-based proteomics analysis of molecular pathways in canine diabetes mellitus after astaxanthin supplementation

Sataporn Phochantachinda, Pongsakorn Photcharatinnakorn, Duangthip Chatchaisak, Walasinee Sakcamduang, Anchana Chansawhang, Shutipen Buranasinsup, Namphung Suemanotham, Boonrat Chantong

published 07 May 2025

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Antithrombotic effect and plasma pharmacochemistry of Justicia Procumbens L

Hui Zhang, Yating Liu, Fengxian Hu, Siyi Chen, Zhoutao Xie, Hezhen Wu, Ting Zhang, Bo Liu

published 30 Apr 2025

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N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade

Nina Germitsch, Tobias Kockmann, Manuela Schnyder, Lucienne Tritten

published 15 Jan 2025

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Integrative omics analysis identifies biomarkers of septic cardiomyopathy

Kexin Cai, Yuqing Luo, Hongyin Chen, Yanfang Dong, Yunyun Su, Chen Lin, Chuanqi Cai, Yikbin Shi, Siming Lin, Guili Lian, Zhihong Lin, Shaodan Feng

published 15 Nov 2024

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