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Complement system

Pre-clinical efficacy of a C4BP hexameric IgG Fc fusion protein against Neisseria gonorrhoeae

Jutamas Shaughnessy, Jintang Du, Mary Wakim Broden, Sunita Gulati, Bo Zheng, Nancy Nowak, Gretchen Telford, Sandy P. Fontes, Y. Tran, Keith L. Wycoff, Kevin J. Whaley, Alison K. Criss, Sanjay Ram

published 25 Aug 2026

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The role of transglutaminase 2 in stabilizing fibrin clots and supporting hemostasis

Paulina Stoklosa, Risa Suzuki, Murielle Golomingi, Bojun Li, Manfred Heller, Kiyotaka Hitomi, Elaissa Trybus Hardy, Wilbur A. Lam, Verena Schroeder

published 05 Aug 2026

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The endurance effort on a mechanical treadmill does not activate the complement system among trained young women

Robert Nowak, Patrizia Proia, Dorota Kostrzewa-Nowak

published 16 Jul 2026

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Plasma C5a and serum C5aR levels in patients with chronic spontaneous urticaria: A single-center case-control study

Thao T. Pham, Minh N. Vu, My H. Le, Doanh H. Le, Thuong V. Nguyen, Phuong T.M. Pham

published 26 Jun 2026

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Expression of melanoma differentiation–associated gene 5 in the epidermis and cutaneous deposition of complement C3 and immunoglobulins in patients with dermatomyositis

Yoshiaki Zaizen, Takuma Koga, Masahiro Tsutsumi, Shinjiro Kaieda, Jun Akiba, Takekuni Nakama, Tomoaki Hoshino

published 08 Jun 2026

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Dengue severity and profiles of complement activation and immune mediators: A multicenter cohort study in Indonesia

Ika Saptarini, Sri Masyeni, Alida Roswita Harahap, Astuti Giantini, Pringgodigdo Nugroho, Agus Handito, Harimat Hendarwan, Adityo Susilo, Sotianingsih Haryanto, Desi Fitriani, R. Tedjo Sasmono, Erni Juwita Nelwan

published 04 Jun 2026

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Unraveling the significance of decorin in endometriosis development through single cell sequencing and experimental approaches

Guansheng Chen, Wenjing Li, Lingyu Liu, Yongjun Wang

published 15 May 2026

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Overexpression of key complement regulators in glioblastoma

Linnea Blomberg, Leonora Raba, Johan Bengzon, Kurt Osther, Henrietta Nittby Redebrandt

published 15 May 2026

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Anaerobic bacteria Cetobacterium sp. nov C33 plays a crucial role in the intestinal microbial balance and regulation of gene expression to immune and metabolic responses in Nile tilapia

Mario Andrés Colorado Gómez, Javier Fernando Melo-Bolívar, Ruth Yolanda Ruíz Pardo, Howard Junca, Juan F. Alzate, Luisa Marcela Villamil Díaz

published 07 May 2026

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Exploring proteomic signatures in sepsis and non-infectious systemic inflammatory response syndrome

Adolfo Ruiz-Sanmartín, Vicent Ribas, David Suñol, Luis Chiscano-Camón, Laura Martín, Iván Bajaña, Juliana Bastida, Nieves Larrosa, Juan José González, María Dolores Carrasco, Núria Canela, Ricard Ferrer, Juan Carlos Ruiz-Rodríguez

published 24 Apr 2026

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An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge

Daniel Palmer, Atieh Shemshadian, Katherine Berman, Ariana Nobles, Graham G. Willsey, Carol Lyn Piazza, Grace Freeman-Gallant, Michael J. Rudolph, Jeff Bourgeois, Linden Hu, David J. Vance, Nicholas J. Mantis

published 12 Mar 2026

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Salmonella enterica persister cells exhibit distinct susceptibility profiles following exposure to human serum and macrophages

Rodrigo Lira Rodrigues, Júlia Abreu da Rosa, Douglas Diefenbach da Cunha, Thaís Lima Nunes, Pedro Maria Abreu Ferreira, Bruno Kendi Makiyama, Florencia María Barbé-Tuana, Sílvia Dias de Oliveira, Carlos Alexandre Sanchez Ferreira

published 06 Mar 2026

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Mixed effects of complement in a chronic murine model of inflammatory erosive arthritis and pulmonary vascular disease

Kiana L. Chen, Stacey Duemmel, Michael Christof, Gaochan Wang, H. Mark Kenney, Marc Nuzzo, Qingfu Xu, Benjamin Korman, Homaira Rahimi

published 05 Feb 2026

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