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Complement activation

A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention

Nehemiah Zewde, Dimitrios Morikis

In vitro generation and bioactivity evaluation of C-reactive protein intermediate

Jian-Min Lv, Ming-Yu Wang

A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer’s disease

Kameran Lashkari, Gianna Teague, [ ... ], Francisco J. López

Changes in N-glycans of IgG4 and its relationship with the existence of hypocomplementemia and individual organ involvement in patients with IgG4-related disease

Naoki Konno, Mitsuru Sugimoto, [ ... ], Hiroshi Watanabe

Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action

Douglas Sheridan, Zhao-Xue Yu, [ ... ], Paul Tamburini

Dimeric IgG complexes from IVIg are incapable of inducing in vitro neutrophil degranulation or complement activation

Iwan Kustiawan, Ninotska I. L. Derksen, [ ... ], Theo Rispens

Hypocomplementemia is associated with worse renal survival in ANCA-positive granulomatosis with polyangiitis and microscopic polyangiitis

Samuel Deshayes, Achille Aouba, [ ... ], Nicolas Martin Silva

The use of the vaccinia virus complement control protein (VCP) in the rat retina

Nilisha Fernando, Riccardo Natoli, [ ... ], Krisztina Valter

The role of complement activation in rhabdomyolysis-induced acute kidney injury

XuDong Huang, Wei Zhao, [ ... ], GuangLi Wu

Hexons from adenovirus serotypes 5 and 48 differentially protect adenovirus vectors from neutralization by mouse and human serum

Andrew W. Harmon, Rituparna Moitra, Zhili Xu, Andrew P. Byrnes

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model

Lorenz Jenny, József Dobó, [ ... ], Verena Schroeder

Reduced order modeling and analysis of the human complement system

Adithya Sagar, Wei Dai, [ ... ], Jeffrey D. Varner

Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice

Ingrid Stroo, Jack Yang, [ ... ], Sacha Zeerleder

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