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Complement activation

Cell-free IgG-aggregates in plasma of patients with chronic lymphocytic leukemia cause chronic activation of the classical complement pathway

Regina Michelis, Tamar Tadmor, Ariel Aviv, Galia Stemer, Rawan Majdob, Lev Shvidel, Mona Shehadeh, Masad Barhoum, Andrei Braester

published 09 Mar 2020

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Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants

Pamela S. Hair, Adrianne I. Enos, Neel K. Krishna, Kenji M. Cunnion

published 31 Dec 2019

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Platelet thrombus formation in eHUS is prevented by anti-MBL2

R. I. Kushak, D. C. Boyle, I. A. Rosales, J. R. Ingelfinger, G. L. Stahl, M. Ozaki, R. B. Colvin, E. F. Grabowski

published 27 Dec 2019

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Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study

Ingrid Hokstad, Gia Deyab, Morten Wang Fagerland, Torstein Lyberg, Gunnbjørg Hjeltnes, Øystein Førre, Stefan Agewall, Tom Eirik Mollnes, Ivana Hollan

published 23 Jul 2019

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Neutrophils from ANCA-associated vasculitis patients show an increased capacity to activate the complement system via the alternative pathway after ANCA stimulation

Sophie Ohlsson, Lisa Holm, Christina Hansson, Susanne M. Ohlsson, Lena Gunnarsson, Åsa Pettersson, Lillemor Skattum

published 19 Jun 2019

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Different mechanisms of serum complement activation in the plasma of common (Chelydra serpentina) and alligator (Macrochelys temminckii) snapping turtles

Sarah Baker, Ethan Kessler, Lancia Darville-Bowleg, Mark Merchant

published 06 Jun 2019

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Genetic strategy to decrease complement activation with adenoviral therapies

Christopher M. Gentile, Anton V. Borovjagin, Jillian R. Richter, Aditi H. Jani, Hongju Wu, Kurt R. Zinn, Jason M. Warram

published 26 Apr 2019

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Stimulation of a protease targeting the LRIM1/APL1C complex reveals specificity in complement-like pathway activation in Anopheles gambiae

Valeria M. Reyes Ruiz, Gregory L. Sousa, Sarah D. Sneed, Katie V. Farrant, George K. Christophides, Michael Povelones

published 08 Apr 2019

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CD46 knock-out using CRISPR/Cas9 editing of hTERT immortalized human cells modulates complement activation

Matthias Wieser, Teresa Francisci, Daniel Lackner, Tilmann Buerckstuemmer, Kamilla Wasner, Wolf Eilenberg, Anton Stift, Markus Wahrmann, Georg A. Böhmig, Johannes Grillari, Regina Grillari-Voglauer

published 08 Apr 2019

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A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity

Regina Michelis, Tamar Tadmor, Masad Barhoum, Mona Shehadeh, Lev Shvidel, Ariel Aviv, Galia Stemer, Najib Dally, Naomi Rahimi-Levene, Mona Yuklea, Andrei Braester

published 02 Jan 2019

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Ficolin-2 binds to serotype 35B pneumococcus as it does to serotypes 11A and 31, and these serotypes cause more infections in older adults than in children

K. Aaron Geno, Brady L. Spencer, Sejong Bae, Moon H. Nahm

published 26 Dec 2018

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Complement inhibition ameliorates blast-induced acute lung injury in rats: Potential role of complement in intracellular HMGB1-mediated inflammation

Yansong Li, Zhangsheng Yang, Mikulas Chavko, Bin Liu, Olawale A. Aderemi, Milomir O. Simovic, Michael A. Dubick, Leopoldo C. Cancio

published 22 Aug 2018

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Influence of citrate concentration on the activation of blood cells in an in vitro dialysis setup

Jakob Gubensek, Karin Strobl, Stephan Harm, Rene Weiss, Tanja Eichhorn, Jadranka Buturovic-Ponikvar, Viktoria Weber, Jens Hartmann

published 13 Jun 2018

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