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Complement activation

Severe COVID-19 in pregnancy has a distinct serum profile, including greater complement activation and dysregulation of serum lipids

Marie Altendahl, Thalia Mok, Christine Jang, Seungjun Yeo, Austin Quach, Yalda Afshar

published 16 Nov 2022

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Noninvasive nasopharyngeal proteomics of COVID-19 patient identify abnormalities related to complement and coagulation cascade and mucosal immune system

Mohamad Ammar Ayass, Wanying Cao, Jin Zhang, Jun Dai, Kevin Zhu, Trivendra Tripathi, Natalya Griko, Victor Pashkov, Lina Abi-Mosleh

published 12 Sep 2022

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Pharmacokinetics and pharmacodynamics of pozelimab alone or in combination with cemdisiran in non-human primates

Kishor Devalaraja-Narashimha, Cong Huang, Marc Cao, Ya Ping Chen, Anna Borodovsky, William C. Olson, Lori G. Morton, Marc W. Retter

published 16 Jun 2022

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A Factor H-Fc fusion protein increases complement-mediated opsonophagocytosis and killing of community associated methicillin-resistant Staphylococcus aureus

Megan A. G. Sage, Katelyn D. Cranmer, Michele L. Semeraro, Shelby Ma, Elena V. Galkina, Y. Tran, Keith L. Wycoff, Julia A. Sharp

published 24 Mar 2022

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Myasthenia gravis complement activity is independent of autoantibody titer and disease severity

Miriam L. Fichtner, Michelle D. Hoarty, Douangsone D. Vadysirisack, Bailey Munro-Sheldon, Richard J. Nowak, Kevin C. O’Connor

published 15 Mar 2022

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Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis

Thao H. P. Nguyen, Ingrid Hokstad, Morten Wang Fagerland, Tom Eirik Mollnes, Ivana Hollan, Mark W. Feinberg, Gunnbjørg Hjeltnes, Gro Ø. Eilertsen, Knut Mikkelsen, Stefan Agewall

published 25 Feb 2022

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Eculizumab in patients with severe coronavirus disease 2019 (COVID-19) requiring continuous positive airway pressure ventilator support: Retrospective cohort study

Piero Ruggenenti, Fabiano Di Marco, Monica Cortinovis, Luca Lorini, Silvia Sala, Luca Novelli, Federico Raimondi, Sara Gastoldi, Miriam Galbusera, Roberta Donadelli, Caterina Mele, Rossella Piras, Marina Noris, Valentina Portalupi, Laura Cappelletti, Camillo Carrara, Federica Tomatis, Silvia Bernardi, Annalisa Perna, Tobia Peracchi, Olimpia Diadei, Ariela Benigni, Giuseppe Remuzzi

published 20 Dec 2021

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Peptide inhibition of acute lung injury in a novel two-hit rat model

Alana C. Sampson, Brittany P. Lassiter, Magdielis Gregory Rivera, Pamela S. Hair, Kaitlyn G. Jackson, Adrianne I. Enos, Turaj Vazifedan, Alice L. Werner, Marshall J. Glesby, Frank A. Lattanzio, Kenji M. Cunnion, Neel K. Krishna

published 28 Oct 2021

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Spatiotemporal dynamics of maximal and minimal EEG spectral power

Melisa Menceloglu, Marcia Grabowecky, Satoru Suzuki

published 20 Jul 2021

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Systemic complement activation levels in Stargardt disease

Patty P. A. Dhooge, Esmee H. Runhart, Catherina H. Z. Li, Corrie M. de Kat Angelino, Carel B. Hoyng, Renate G. van der Molen, Anneke I. den Hollander

published 25 Jun 2021

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Tubular cell damage may be the earliest sign of renal extrahepatic manifestation caused by Hepatitis C

Kati Kaartinen, Sauli Vuoti, Eero Honkanen, Eliisa Löyttyniemi, Ravinder Singh, Martti Färkkilä

published 07 May 2021

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Treatment of Plasmodium falciparum merozoites with the protease inhibitor E64 and mechanical filtration increases their susceptibility to complement activation

José A. Stoute, Mary E. Landmesser, Sergei Biryukov

published 21 Aug 2020

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Complement inhibitor Crry expression in mouse placenta is essential for maintaining normal blood pressure and fetal growth

Manu Banadakoppa, Kathleen Pennington, Meena Balakrishnan, Chandra Yallampalli

published 03 Aug 2020

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