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Colitis

Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis

Lei Guo, Jun Ge, Li Cheng, Xinyi Zhang, Zhengzheng Wu, Meili Liu, Hanmei Jiang, Wei Gong, Yi Liu

published 17 Dec 2025

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Targeted virome deep sequencing reveals frequent herpesvirus detection in intestinal biopsies of inflammatory bowel disease patients

Jennifer-Natalia Vásquez, Pedro Doncel, Juan Camacho, Estrella Ruiz, Vanessa Recio, David Tarragó

published 11 Dec 2025

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Butyrate ameliorates DSS-induced ulcerative colitis in mice by facilitating autophagy in intestinal epithelial cells and modulating the gut microbiota through blocking the PI3K-AKT-mTOR pathway

Ruifang Li, Yan Sun, Drolma Kelsang, Mingzhi Feng, Hanhui Cai, Jun Zhang

published 11 Dec 2025

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A multi-mineral intervention to improve disease-related and mechanistic biomarkers in ulcerative colitis patients: Results from a randomized trial

Muhammad N. Aslam, Danielle Kim Turgeon, Henry D. Appelman, Ryan Stidham, Shannon McClintock, Ron Allen, Gillian Moraga, Isabelle Harber, Kara J. Jencks, Molly M. McNeely, Ananda Sen, Karl J. Jepsen, James Varani

published 08 Dec 2025

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Pharmacokinetic profiles of Moutan Cortex after single and repeated administration in a dinitrobenzene sulfonic acid-induced colitis model

Jin-Hwa Kim, Ji-Soo Jeong, Jeong-Won Kim, Eun-Hye Chung, Su-Ha Lee, Je-Won Ko, Youn-Hwan Hwang, Tae-Won Kim

published 02 Dec 2025

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Second-line treatment strategies of ulcerative colitis after conventional therapy failure: A systematic review and network meta-analysis of randomized controlled trials

Yanan Xu, Wenshuo Jiang, Meizhu Jiang, Bin Zhu, Jiping Huo, Mingfen Wu, Li Yang

published 01 Dec 2025

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A multilayered genetic structure analysis between inflammatory bowel disease and bone density/osteoporosis

Mengting Qin, Xinhong Liu, Qinghua Luo, Ruyun Cai

published 20 Nov 2025

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Integrative machine learning and multi-omics framework identifies shared biomarkers for rheumatoid arthritis and ulcerative colitis

Meili Liu, Jun Ge, Lei Guo, Zhengzheng Wu, Zimo Cheng, Zenggen Liu, Yi Liu

published 10 Nov 2025

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Elucidation and application of the neuroimmune axis between depression and autoimmune diseases: A genome wide and cohort study

Fu Sun, Shirong Hui, Bin Gong, Jinhua Gu, Peng Huang

published 10 Nov 2025

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The protective role of Lactobacillus reuteri in a DSS-induced ulcerative colitis mouse model

Mohsen Nazari, Rezvan Goodarzi, Atefeh Yazdan Panah, Iraj Amiri, Yasser Bagheri, Babak Asghari

published 06 Nov 2025

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Unveiling and verification of mitochondria-related genes as potential diagnostic biomarkers in ulcerative colitis based on bioinformatics analysis and experimental validation

Hongliang Chen, Ning Li, Xuerong Liu, Mingyu Ran, Xinyu Geng, Jihan Qi, Jiawei Qiu, Xueyu Cang, Shiling Huang, Yingying Tian, Ram Prasad Chaulagain, Shizhu Jin

published 04 Nov 2025

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Significance of the drug-induced lymphocyte stimulation test for various oral mesalamines in ulcerative colitis with mesalamine intolerance

Akira Madarame, Masakatsu Fukuzawa, Kumiko Uchida, Tadashi Ichimiya, Sakiko Naito, Yoshiya Yamauchi, Takashi Morise, Yasuyuki Kagawa, Takahiro Muramatsu, Takao Itoi

published 30 Oct 2025

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Sequencing Therapy for Optimal Response in Mirikizumab (STORM)-study: A tertiary referral center study on patients with therapy-refractory ulcerative colitis

Alica Kubesch, Raul Lande, Anna Leutgöb, Karima Farrag, Iulia Dahmer, Katharina Stratmann-Vollrath, Antje Dienethal, Florian Alexander Michael, Kathrin Sprinzl, Stefan Zeuzem, Irina Blumenstein

published 24 Oct 2025

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