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Colchicine

Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations

Bajarang Vasant Kumbhar, Anubhaw Borogaon, Dulal Panda, Ambarish Kunwar

published 26 May 2016

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Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301

Avijeet Chopra, Michael J. Bond, Marina Bleiler, Michelle Yeagley, Dennis Wright, Charles Giardina

published 20 Apr 2016

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Morin, a Bioflavonoid Suppresses Monosodium Urate Crystal-Induced Inflammatory Immune Response in RAW 264.7 Macrophages through the Inhibition of Inflammatory Mediators, Intracellular ROS Levels and NF-κB Activation

Chitra Dhanasekar, Sowmiya Kalaiselvan, Mahaboobkhan Rasool

published 28 Dec 2015

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Angiotensin II Type 1 Receptor-Mediated Electrical Remodeling in Mouse Cardiac Myocytes

Jeremy Kim, Junyuan Gao, Ira S. Cohen, Richard T. Mathias

published 02 Oct 2015

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A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells

Chun-Te Ho, Yu-Jia Chang, Li-Xi Yang, Po-Li Wei, Tsan-Zon Liu, Jun-Jen Liu

published 10 Sep 2015

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Adherence to the 2012 American College of Rheumatology (ACR) Guidelines for Management of Gout: A Survey of Brazilian Rheumatologists

Ana Beatriz Vargas-Santos, Geraldo da Rocha Castelar-Pinheiro, Evandro Silva Freire Coutinho, H. Ralph Schumacher Jr., Jasvinder A. Singh, Naomi Schlesinger

published 14 Aug 2015

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A New Synthetic Amphiploid (AADDAA) between Gossypium hirsutum and G. arboreum Lays the Foundation for Transferring Resistances to Verticillium and Drought

Yu Chen, Yingying Wang, Ting Zhao, Jianwei Yang, Shouli Feng, Wajad Nazeer, Tianzhen Zhang, Baoliang Zhou

published 10 Jun 2015

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Synthesis and Biological Evaluation of 3-Alkyl-1,5-Diaryl-1H-Pyrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative Activity

Qile Xu, Huan Qi, Maolin Sun, Daiying Zuo, Xuewei Jiang, Zhiyong Wen, Zhiwei Wang, Yingliang Wu, Weige Zhang

published 10 Jun 2015

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Identification of Disease-Promoting HLA Class I and Protective Class II Modifiers in Japanese Patients with Familial Mediterranean Fever

Michio Yasunami, Hitomi Nakamura, Kazunaga Agematsu, Akinori Nakamura, Masahide Yazaki, Dai Kishida, Akihiro Yachie, Tomoko Toma, Junya Masumoto, Hiroaki Ida, Tomohiro Koga, Atsushi Kawakami, Katsumi Eguchi, Hiroshi Furukawa, Tadashi Nakamura, Minoru Nakamura, Kiyoshi Migita

published 14 May 2015

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Suprafenacine, an Indazole-Hydrazide Agent, Targets Cancer Cells Through Microtubule Destabilization

Bo-Hwa Choi, Souvik Chattopadhaya, Le Nguyen Thanh, Lin Feng, Quoc Toan Nguyen, Chuan Bian Lim, Amaravadhi Harikishore, Ravi Prakash Reddy Nanga, Nagakumar Bharatham, Yan Zhao, Xuewei Liu, Ho Sup Yoon

published 29 Oct 2014

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Aneugenic Effects of Epirubicin in Somatic and Germinal Cells of Male Mice

Sabry Mohamed Attia, Sheikh Fayaz Ahmad, Radwa Mohamed Okash, Saleh Abdulrahman Bakheet

published 10 Oct 2014

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The Spindle Matrix Protein, Chromator, Is a Novel Tubulin Binding Protein That Can Interact with Both Microtubules and Free Tubulin

Changfu Yao, Chao Wang, Yeran Li, Yun Ding, Uttama Rath, Saheli Sengupta, Jack Girton, Kristen M. Johansen, Jørgen Johansen

published 29 Jul 2014

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The Effect of Antifibrotic Drugs in Rat Precision-Cut Fibrotic Liver Slices

Inge M. Westra, Dorenda Oosterhuis, Geny M. M. Groothuis, Peter Olinga

published 22 Apr 2014

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