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Chromatin modification

A novel family of beta mixture models for the differential analysis of DNA methylation data: An application to prostate cancer

Koyel Majumdar, Romina Silva, Antoinette Sabrina Perry, Ronald William Watson, Andrea Rau, Florence Jaffrezic, Thomas Brendan Murphy, Isobel Claire Gormley

published 11 Dec 2024

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Regulation of reactive oxygen molecules in pakchoi by histone acetylation modifications under Cd stress

Xiaoqun Cao, Ming Zhang, Xufeng Xiao, Fengrui Yin, Yuekeng Yao, Meilan Sui, Yifan Hu, Yan Xiang, Liangdeng Wang

published 20 Nov 2024

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Generation of isogenic models of Angelman syndrome and Prader-Willi syndrome in CRISPR/Cas9-engineered human embryonic stem cells

Rachel B. Gilmore, Dea Gorka, Christopher E. Stoddard, Pooja Sonawane, Justin Cotney, Stormy J. Chamberlain

published 01 Nov 2024

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iDNA-ITLM: An interpretable and transferable learning model for identifying DNA methylation

Xia Yu, Cui Yani, Zhichao Wang, Haixia Long, Rao Zeng, Xiling Liu, Bilal Anas, Jia Ren

published 31 Oct 2024

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A study of the clinical significance of mSEPT9 in monitoring recurrence and prognosis in patients with surgically treated colorectal cancer

Rong Li, Jiaojiao Chen, Xin Shen, Yanping Lin, Jiadai Tang, Guangrui Xiong, Ke Zhang, Mengying Xiang, Lin Xie, Fengdi Hu

published 28 Oct 2024

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Epigenetic aging differentially impacts breast cancer risk by self-reported race

Yanning Wu, Megan E. Miller, Hannah L. Gilmore, Cheryl L. Thompson, Fredrick R. Schumacher

published 24 Oct 2024

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Voluntary wheel running exercise rescues behaviorally-evoked acetylcholine efflux in the medial prefrontal cortex and epigenetic changes in ChAT genes following adolescent intermittent ethanol exposure

Matthew J. Fecik, Polliana T. Nunes, Ryan P. Vetreno, Lisa M. Savage

published 22 Oct 2024

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Enhanced thermal stability enables human mismatch-specific thymine–DNA glycosylase to catalyse futile DNA repair

Diana Manapkyzy, Botagoz Joldybayeva, Alexander A. Ishchenko, Bakhyt T. Matkarimov, Dmitry O. Zharkov, Sabira Taipakova, Murat K. Saparbaev

published 18 Oct 2024

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Screening of differential gene expression patterns through survival analysis for diagnosis, prognosis and therapies of clear cell renal cell carcinoma

Alvira Ajadee, Sabkat Mahmud, Md. Bayazid Hossain, Reaz Ahmmed, Md. Ahad Ali, Md. Selim Reza, Saroje Kumar Sarker, Md. Nurul Haque Mollah

published 30 Sep 2024

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Cell-type specific methylation changes in the newborn child associated to obstetric pain relief

Charles J. Tran, Thomas L. Campbell, Ralen H. Johnson, Lin Y. Xie, Christina M. Hultman, Edwin J. C. G. van den Oord, Karolina A. Aberg

published 19 Sep 2024

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Biochemical reconstitution of heat-induced mutational processes

Tomohiko Sugiyama

published 17 Sep 2024

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Differential expression and regulation of ADAD1, DMRTC2, PRSS54, SYCE1, SYCP1, TEX101, TEX48, and TMPRSS12 gene profiles in colon cancer tissues and their in vitro response to epigenetic drugs

Mikhlid H. Almutairi, Turki M. Alrubie, Alaa T. Alshareeda, Nada Albarakati, Alhomidi Almotiri, Abdullah M. Alamri, Bader O. Almutairi, Mohammad Alanazi

published 29 Aug 2024

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Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review

Alina Liebich, Shenglin Zheng, Theresa Schachner, Jacqueline Mair, Mia Jovanova, Falk Müller-Riemenschneider, Tobias Kowatsch

published 19 Aug 2024

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