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Chondrocytes

Screening potential anti-osteoarthritis compounds using molecular docking based on MAPK and NFκB pathways and validating their anti-osteoarthritis effect

Tian-Wang Zhu, Yu Zheng, Rui-Xin Li

Non-targeted metabolomic study in plasma in rats with post-traumatic osteoarthritis model

Peng-fei Han, Xi-yong Li, [ ... ], Yuan Li

Dehydroepiandrosterone inhibits ADAMTS expression via an ERK-dependent mechanism in chondrocytes

Kai Huang, Lin Cheng, [ ... ], Haili Cai

Association between serum Klotho and the prevalence of osteoarthritis: A cross-sectional study from NHANES 2007–2016

Yue Qiu, Huangyi Yin, [ ... ], Jia Li

A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery

Philip R. Coryell, Paul B. Hardy, [ ... ], Richard F. Loeser

Picroside II suppresses chondrocyte pyroptosis through MAPK/NF-κB/NLRP3 signaling pathway alleviates osteoarthritis

Fanchen Wang, Jiacong Xiao, [ ... ], Chi Zhou

Blocking IL-33 decelerates cartilage degeneration in knee osteoarthritis through mice model

Fan Wu, Siyuan Zhang, [ ... ], Kangxiang Zhu

Anti-inflammatory effect of the combined treatment of LMT-28 and kaempferol in a collagen-induced arthritis mouse model

Young-Jin Jeong, Sun-Ae Park, [ ... ], Tae-Hwe Heo

Integration of metabolomics and transcriptomics provides insights into the molecular mechanism of temporomandibular joint osteoarthritis

Palati Tuerxun, Takkun Ng, Ke Zhao, Ping Zhu

Mume Fructus reduces interleukin-1 beta-induced cartilage degradation via MAPK downregulation in rat articular chondrocytes

Doo Ri Park, Bo Ram Choi, [ ... ], In-Hyuk Ha

Overexpression of RAD54L attenuates osteoarthritis by suppressing the HIF-1α/VEGF signaling pathway: Bioinformatics analysis and experimental validation

Zhengnan Li, Lifeng Xie, [ ... ], Jun Tao

Protective effects of ectoine on articular chondrocytes and cartilage in rats for treating osteoarthritis

Peng Li, Yong Huang, [ ... ], Zhanjun Shi

Duhuo Jisheng Decoction regulates intracellular zinc homeostasis by enhancing autophagy via PTEN/Akt/mTOR pathway to improve knee cartilage degeneration

Ye-Hui Wang, Yi Zhou, [ ... ], Quan Xie

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