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CHO cells

Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production

Gargi Roy, Shu Zhang, Lina Li, Eileen Higham, Herren Wu, Marcello Marelli, Michael A. Bowen

published 23 Aug 2017

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Expression and functional implications of the renal apelinergic system in rodents

Anne-Marie O’Carroll, Sabrine Salih, Philip R. Griffiths, Aarifah Bijabhai, Mark A. Knepper, Stephen J. Lolait

published 17 Aug 2017

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Metabolic engineering of CHO cells for the development of a robust protein production platform

Sanjeev Kumar Gupta, Santosh K. Srivastava, Ankit Sharma, Vaibhav H. H. Nalage, Darshita Salvi, Hiralal Kushwaha, Nikhil B. Chitnis, Pratyoosh Shukla

published 01 Aug 2017

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A high seroprevalence of antibodies to pertussis toxin among Japanese adults: Qualitative and quantitative analyses

Takumi Moriuchi, Nao Otsuka, Yukihiro Hiramatsu, Keigo Shibayama, Kazunari Kamachi

published 10 Jul 2017

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The short mRNA isoform of the immunoglobulin superfamily, member 1 gene encodes an intracellular glycoprotein

Ying Wang, Emilie Brûlé, Tanya Silander, Beata Bak, Sjoerd D. Joustra, Daniel J. Bernard

published 07 Jul 2017

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Monoclonal antibodies expression improvement in CHO cells by PiggyBac transposition regarding vectors ratios and design

Samira Ahmadi, Fatemeh Davami, Noushin Davoudi, Fatemeh Nematpour, Maryam Ahmadi, Saeedeh Ebadat, Kayhan Azadmanesh, Farzaneh Barkhordari, Fereidoun Mahboudi

published 29 Jun 2017

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HEK293T cell lines defective for O-linked glycosylation

James M. Termini, Zachary A. Silver, Bryony Connor, Aristotelis Antonopoulos, Stuart M. Haslam, Anne Dell, Ronald C. Desrosiers

published 27 Jun 2017

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Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity

Ainoleena Turku, Maiju K. Rinne, Gustav Boije af Gennäs, Henri Xhaard, Dan Lindholm, Jyrki P. Kukkonen

published 02 Jun 2017

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T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα

Yijun Shen, Gang Li, Chunying Gu, Ben Chen, Aihua Chen, Hua Li, Bei Gao, Chencai Liang, Jingsong Wu, Tong Yang, Li Jin, Yong Su

published 19 May 2017

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Model-based analysis of N-glycosylation in Chinese hamster ovary cells

Frederick J. Krambeck, Sandra V. Bennun, Mikael R. Andersen, Michael J. Betenbaugh

published 09 May 2017

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TRPV1 activation power can switch an action mode for its polypeptide ligands

Maxim V. Nikolaev, Natalia A. Dorofeeva, Margarita S. Komarova, Yuliya V. Korolkova, Yaroslav A. Andreev, Irina V. Mosharova, Eugene V. Grishin, Denis B. Tikhonov, Sergey A. Kozlov

published 05 May 2017

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Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D₂

Nanae Nagata, Hiroko Iwanari, Hidetoshi Kumagai, Osamu Kusano-Arai, Yuichi Ikeda, Kosuke Aritake, Takao Hamakubo, Yoshihiro Urade

published 10 Apr 2017

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Comprehensive N-Glycan Profiling of Cetuximab Biosimilar Candidate by NP-HPLC and MALDI-MS

Sheng Liu, Wenjie Gao, Yao Wang, Zhenyu He, Xiaojun Feng, Bi-Feng Liu, Xin Liu

published 10 Jan 2017

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