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Cell lines

Gypenosides Synergistically Enhances the Anti-Tumor Effect of 5-Fluorouracil on Colorectal Cancer In Vitro and In Vivo: A Role for Oxidative Stress-Mediated DNA Damage and p53 Activation

Lulu Kong, Xiaobing Wang, Kun Zhang, Wenjuan Yuan, Qiwen Yang, Jianping Fan, Pan Wang, Quanhong Liu

published 14 Sep 2015

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Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell Differentiation

Qingfeng Ding, Mei Zhao, Bolan Yu, Chuan Bai, Zhaofeng Huang

published 14 Sep 2015

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Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells

Luyuan Li, Ana C. Paz, Breelyn A. Wilky, Britt Johnson, Karina Galoian, Andrew Rosenberg, Guozhi Hu, Gabriel Tinoco, Olaf Bodamer, Jonathan C. Trent

published 14 Sep 2015

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Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids

Cristina E. Rodríguez, Sara I. Reidel, Elisa D. Bal de Kier Joffé, Maria A. Jasnis, Gabriel L. Fiszman

published 11 Sep 2015

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Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR

Nívia Carolina Nogueira-Paiva, Paula Melo de Abreu Vieira, Larissa Maris Rezende Oliveri, Kátia da Silva Fonseca, Gwenaelle Pound-Lana, Maykon Tavares de Oliveira, Marta de Lana, Vanja Maria Veloso, Alexandre Barbosa Reis, Washington Luiz Tafuri, Cláudia Martins Carneiro

published 11 Sep 2015

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G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound

Maia Cabrera, Natalia Gomez, Federico Remes Lenicov, Emiliana Echeverría, Carina Shayo, Albertina Moglioni, Natalia Fernández, Carlos Davio

published 11 Sep 2015

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KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway

Dalsan You, Yunlim Kim, Myoung Jin Jang, Chunwoo Lee, In Gab Jeong, Yong Mee Cho, Jung Jin Hwang, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim

published 09 Sep 2015

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Transcriptional Analysis of the Conjugal Transfer Genes of Rickettsia bellii RML 369-C

Chan C. Heu, Timothy J. Kurtti, Curtis M. Nelson, Ulrike G. Munderloh

published 09 Sep 2015

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Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension

Laura J. Goodall, Milan Ovecka, Daniel Rycroft, Sarah L. Friel, Andrew Sanderson, Prafull Mistry, Marie L. Davies, A. Allart Stoop

published 09 Sep 2015

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Human Herpesvirus-6 U14 Induces Cell-Cycle Arrest in G2/M Phase by Associating with a Cellular Protein, EDD

Junko Mori, Akiko Kawabata, Huamin Tang, Kenjiro Tadagaki, Hiroyuki Mizuguchi, Kazumichi Kuroda, Yasuko Mori

published 04 Sep 2015

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Negative Regulation of p21^Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability

Lingling Cao, Jian Ding, Liguo Dong, Jiayao Zhao, Jiaming Su, Lingyao Wang, Yi Sui, Tong Zhao, Fei Wang, Jingji Jin, Yong Cai

published 04 Sep 2015

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Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function

Zhi Liu, Shuang Ding, Konstantin Kropachev, Jia Lei, Shantu Amin, Suse Broyde, Nicholas E. Geacintov

published 04 Sep 2015

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A Single Dynamic Metabolic Model Can Describe mAb Producing CHO Cell Batch and Fed-Batch Cultures on Different Culture Media

Julien Robitaille, Jingkui Chen, Mario Jolicoeur

published 02 Sep 2015

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