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Cell disruption

Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes

Thomas A. Ward, Peter J. McHugh, Stephen T. Durant

published 19 Jun 2017

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Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

Jui-Hua Hsieh, Ruili Huang, Ja-An Lin, Alexander Sedykh, Jinghua Zhao, Raymond R. Tice, Richard S. Paules, Menghang Xia, Scott S. Auerbach

published 22 May 2017

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The burden of trisomy 21 disrupts the proteostasis network in Down syndrome

Stefanos Aivazidis, Christina M. Coughlan, Abhishek K. Rauniyar, Hua Jiang, L. Alexander Liggett, Kenneth N. Maclean, James R. Roede

published 21 Apr 2017

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Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling

Hyun Beom Song, Hyoung-Oh Jun, Jin Hyoung Kim, Young-Ha Lee, Min-Ho Choi, Jeong Hun Kim

published 13 Apr 2017

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Quantification of Plasmid Copy Number with Single Colour Droplet Digital PCR

Magdalena Plotka, Mateusz Wozniak, Tadeusz Kaczorowski

published 13 Jan 2017

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Confined Mobility of TonB and FepA in Escherichia coli Membranes

Yoriko Lill, Lorne D. Jordan, Chuck R. Smallwood, Salete M. Newton, Markus A. Lill, Phillip E. Klebba, Ken Ritchie

published 09 Dec 2016

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Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway

Joshua H. K. Tam, M. Rebecca Cobb, Claudia Seah, Stephen H. Pasternak

published 24 Oct 2016

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The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System

Shingo Iwasa, Naoko Sato, Chao-Wen Wang, Yun-Hsin Cheng, Hayato Irokawa, Gi-Wook Hwang, Akira Naganuma, Shusuke Kuge

published 26 Jul 2016

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Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms

Gregory V. Schimizzi, Meghan T. Maher, Andrew J. Loza, Gregory D. Longmore

published 25 Jul 2016

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Regulation of Thrombin-Induced Lung Endothelial Cell Barrier Disruption by Protein Kinase C Delta

Lishi Xie, Eddie T. Chiang, Xiaomin Wu, Gabriel T. Kelly, Prasad Kanteti, Patrick A. Singleton, Sara M. Camp, Tingting Zhou, Steven M. Dudek, Viswanathan Natarajan, Ting Wang, Steven M. Black, Joe G. N. Garcia, Jeffrey R. Jacobson

published 21 Jul 2016

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Biochemical Preparation of Cell Extract for Cell-Free Protein Synthesis without Physical Disruption

Kei Fujiwara, Nobuhide Doi

published 29 Apr 2016

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Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo

Michael Zhang, Gregor Hutter, Suzana A. Kahn, Tej D. Azad, Sharareh Gholamin, Chelsea Y. Xu, Jie Liu, Achal S. Achrol, Chase Richard, Pia Sommerkamp, Matthew Kenneth Schoen, Melissa N. McCracken, Ravi Majeti, Irving Weissman, Siddhartha S. Mitra, Samuel H. Cheshier

published 19 Apr 2016

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A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity

Neil M. O’Brien-Simpson, Namfon Pantarat, Troy J. Attard, Katrina A. Walsh, Eric C. Reynolds

published 17 Mar 2016

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